Isolation and Identification of the Antimicrobial Agent Beauvericin from the Endophytic Fusarium oxysporum 5-19 with NMR and ESI-MSMS
Joint Authors
Zhang, Huawei
Ruan, Chuanfen
Bai, Xuelian
Zhang, Miao
Zhu, Shuangshuang
Jiang, Yingying
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Endophytic microbe has been proved to be one of rich sources of bioactive natural products with potential application for new drug and pesticide discovery.
One cyclodepsipeptide, beauvericin, was firstly isolated from the fermentation broth of Fusarium oxysporum 5-19 endophytic on Edgeworthia chrysantha Linn.
Its chemical structure was unambiguously identified by a combination of spectroscopic methods, such as HRESI-MS and 1H and 13C NMR.
ESI-MS/MS was successfully used to elucidate the splitting decomposition route of the positive molecule ion of beauvericin.
Antimicrobial results showed that this cyclodepsipeptide had inhibitory effect on three human pathogenic microbes, Candida albicans, Escherichia coli, and Staphylococcus aureus.
In particular, beauvericin exhibited the strongest antimicrobial activity against S.
aureus with MIC values of 3.91 μM, which had similar effect with that of the positive control amoxicillin.
American Psychological Association (APA)
Zhang, Huawei& Ruan, Chuanfen& Bai, Xuelian& Zhang, Miao& Zhu, Shuangshuang& Jiang, Yingying. 2016. Isolation and Identification of the Antimicrobial Agent Beauvericin from the Endophytic Fusarium oxysporum 5-19 with NMR and ESI-MSMS. BioMed Research International،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1096823
Modern Language Association (MLA)
Zhang, Huawei…[et al.]. Isolation and Identification of the Antimicrobial Agent Beauvericin from the Endophytic Fusarium oxysporum 5-19 with NMR and ESI-MSMS. BioMed Research International No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1096823
American Medical Association (AMA)
Zhang, Huawei& Ruan, Chuanfen& Bai, Xuelian& Zhang, Miao& Zhu, Shuangshuang& Jiang, Yingying. Isolation and Identification of the Antimicrobial Agent Beauvericin from the Endophytic Fusarium oxysporum 5-19 with NMR and ESI-MSMS. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1096823
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096823