Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair
Joint Authors
Madry, Henning
Rey-Rico, Ana
Cucchiarini, Magali
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-23
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Delivery of bioactive factors is a very valuable strategy for articular cartilage repair.
Nevertheless, the direct supply of such biomolecules is limited by several factors including rapid degradation, the need for supraphysiological doses, the occurrence of immune and inflammatory responses, and the possibility of dissemination to nontarget sites that may impair their therapeutic action and raise undesired effects.
The use of controlled delivery systems has the potential of overcoming these hurdles by promoting the temporal and spatial presentation of such factors in a defined target.
Hydrogels are promising materials to develop delivery systems for cartilage repair as they can be easily loaded with bioactive molecules controlling their release only where required.
This review exposes the most recent technologies on the design of hydrogels as controlled delivery platforms of bioactive molecules for cartilage repair.
American Psychological Association (APA)
Rey-Rico, Ana& Madry, Henning& Cucchiarini, Magali. 2016. Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair. BioMed Research International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1096830
Modern Language Association (MLA)
Rey-Rico, Ana…[et al.]. Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair. BioMed Research International No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1096830
American Medical Association (AMA)
Rey-Rico, Ana& Madry, Henning& Cucchiarini, Magali. Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1096830
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096830