Magnetic Resonance Imaging of Postoperative Fracture Healing Process without Metal Artifact: A Preliminary Report of a Novel Animal Model
Joint Authors
Sun, Yu
Jin, Zhe
Yu, Guibo
Guan, Yuheng
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Early radiological diagnosis and continual monitoring are of ultimate importance for timely treatment of delayed union, nonunion, and infection after bone fracture surgery.
Although magnetic resonance imaging (MRI) could provide superior detailed images compared with X-ray and computed tomography (CT) without ionizing radiation, metal implants used for fracture fixation lead to abundant artifacts on MRI and thus prohibit accurate interpretation.
The authors develop a novel intramedullary fixation model of rat femoral fracture using polyetheretherketone (PEEK) threaded rods and investigate its feasibility for in vivo MRI monitoring of the fracture healing process without artifact.
Methods.
Femoral fractures of 3 adult male Sprague-Dawley rats were fixed with intramedullary PEEK threaded rods.
X-ray and MRI examinations were performed at day 7 postoperatively.
Radiological images were analyzed for the existence of artifact interruption and postoperative changes in bone and peripheral soft tissue.
Results.
Postoperative plain film revealed no loss of reduction.
MRI images illustrated the whole length of femur and peripheral tissue without artifact interruption, and the cortical bone, implanted PEEK rod, and soft tissue were clearly illustrated.
Conclusion.
This preliminary study introduced a novel rat model for in vivo MRI monitoring of the fracture healing process without metal artifact, by using intramedullary fixation of femur with PEEK threaded rod.
American Psychological Association (APA)
Jin, Zhe& Guan, Yuheng& Yu, Guibo& Sun, Yu. 2016. Magnetic Resonance Imaging of Postoperative Fracture Healing Process without Metal Artifact: A Preliminary Report of a Novel Animal Model. BioMed Research International،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1096881
Modern Language Association (MLA)
Jin, Zhe…[et al.]. Magnetic Resonance Imaging of Postoperative Fracture Healing Process without Metal Artifact: A Preliminary Report of a Novel Animal Model. BioMed Research International No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1096881
American Medical Association (AMA)
Jin, Zhe& Guan, Yuheng& Yu, Guibo& Sun, Yu. Magnetic Resonance Imaging of Postoperative Fracture Healing Process without Metal Artifact: A Preliminary Report of a Novel Animal Model. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1096881
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096881