Effect of 48 h Fasting on Autonomic Function, Brain Activity, Cognition, and Mood in Amateur Weight Lifters

Abstract EN

Objectives.

The acute fasting-induced cardiovascular autonomic response and its effect on cognition and mood remain debatable.

Thus, the main purpose of this study was to estimate the effect of a 48 h, zero-calorie diet on autonomic function, brain activity, cognition, and mood in amateur weight lifters.

Methods.

Nine participants completed a 48 h, zero-calorie diet program.

Cardiovascular autonomic function, resting frontal brain activity, cognitive performance, and mood were evaluated before and after fasting.

Results.

Fasting decreased (p<0.05) weight, heart rate, and systolic blood pressure, whereas no changes were evident regarding any of the measured heart rate variability indices.

Fasting decreased (p<0.05) the concentration of oxygenated hemoglobin and improved (p<0.05) mental flexibility and shifting set, whereas no changes were observed in working memory, visuospatial discrimination, and spatial orientation ability.

Fasting also increased (p<0.05) anger, whereas other mood states were not affected by it.

Conclusions.

48 h fasting resulted in higher parasympathetic activity and decreased resting frontal brain activity, increased anger, and improved prefrontal-cortex-related cognitive functions, such as mental flexibility and set shifting, in amateur weight lifters.

In contrast, hippocampus-related cognitive functions were not affected by it.