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Biological Activities of Aerial Parts Extracts of Euphorbia characias
Joint Authors
Tramontano, Enzo
Cosentino, Sofia
Medda, Rosaria
Esposito, Francesca
Montoro, Paola
Tuberoso, Carlo Ignazio Giovanni
Pisano, Maria Barbara
Viale, Silvia
Corona, Angela
Pintus, Francesca
Spanò, Delia
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The aim of the present study was to evaluate antioxidant, antimicrobial, anti-HIV, and cholinesterase inhibitory activities of aqueous and alcoholic extracts from leaves, stems, and flowers of Euphorbia characias.
The extracts showed a high antioxidant activity and were a good source of total polyphenols and flavonoids.
Ethanolic extracts from leaves and flowers displayed the highest inhibitory activity against acetylcholinesterase and butyrylcholinesterase, showing potential properties against Alzheimer’s disease.
Antimicrobial assay showed that leaves and flowers extracts were active against all Gram-positive bacteria tested.
The ethanolic leaves extract appeared to have the strongest antibacterial activity against Bacillus cereus with MIC value of 312.5 μg/mL followed by Listeria monocytogenes and Staphylococcus aureus that also exhibited good sensitivity with MIC values of 1250 μg/mL.
Moreover, all the extracts possessed anti-HIV activity.
The ethanolic flower extract was the most potent inhibitor of HIV-1 RT DNA polymerase RNA-dependent and Ribonuclease H with IC50 values of 0.26 and 0.33 μg/mL, respectively.
The LC-DAD metabolic profile showed that ethanolic leaves extract contains high levels of quercetin derivatives.
This study suggests that Euphorbia characias extracts represent a good source of natural bioactive compounds which could be useful for pharmaceutical application as well as in food system for the prevention of the growth of food-borne bacteria and to extend the shelf-life of processed foods.
American Psychological Association (APA)
Pisano, Maria Barbara& Cosentino, Sofia& Viale, Silvia& Spanò, Delia& Corona, Angela& Esposito, Francesca…[et al.]. 2016. Biological Activities of Aerial Parts Extracts of Euphorbia characias. BioMed Research International،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1096908
Modern Language Association (MLA)
Pisano, Maria Barbara…[et al.]. Biological Activities of Aerial Parts Extracts of Euphorbia characias. BioMed Research International No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1096908
American Medical Association (AMA)
Pisano, Maria Barbara& Cosentino, Sofia& Viale, Silvia& Spanò, Delia& Corona, Angela& Esposito, Francesca…[et al.]. Biological Activities of Aerial Parts Extracts of Euphorbia characias. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1096908
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096908