An Ash1-Like Protein MoKMT2H Null Mutant Is Delayed for Conidium Germination and Pathogenesis in Magnaporthe oryzae
Joint Authors
Cao, Zhaojun
Yin, Yue
Sun, Xuan
Han, Jun
Sun, Qing peng
Lu, Min
Pan, Jinbao
Wang, Weixiang
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Ash1 is a known H3K36-specific histone demethylase that is required for normal Hox gene expression and fertility in Drosophila and mammals.
However, little is known about the expression and function of the fungal ortholog of Ash1 in phytopathogenic fungus Magnaporthe oryzae.
Here we report that MoKMT2H, an Ash1-like protein, is required for conidium germination and virulence in rice.
We obtained MoKMT2H null mutant ( Δ MoKMT2H) using a target gene replacement strategy.
In the Δ MoKMT2H null mutants, global histone methyltransferase modifications (H3K4me3, H3K9me3, H3K27me3, and H3K36me2/3) of the genome were unaffected.
The Δ MoKMT2H mutants showed no defect in vegetative hyphal growth, conidium morphology, conidiation, or disease lesion formation on rice leaves.
However, the MoKMT2H deletion mutants were delayed for conidium germination and consequently had decreased virulence.
Taken together, our results indicated that MoKMT2H plays an important role in conidium germination during appressorium formation in the rice blast fungus and perhaps other pathogenic plant fungi.
American Psychological Association (APA)
Cao, Zhaojun& Yin, Yue& Sun, Xuan& Han, Jun& Sun, Qing peng& Lu, Min…[et al.]. 2016. An Ash1-Like Protein MoKMT2H Null Mutant Is Delayed for Conidium Germination and Pathogenesis in Magnaporthe oryzae. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1096913
Modern Language Association (MLA)
Cao, Zhaojun…[et al.]. An Ash1-Like Protein MoKMT2H Null Mutant Is Delayed for Conidium Germination and Pathogenesis in Magnaporthe oryzae. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1096913
American Medical Association (AMA)
Cao, Zhaojun& Yin, Yue& Sun, Xuan& Han, Jun& Sun, Qing peng& Lu, Min…[et al.]. An Ash1-Like Protein MoKMT2H Null Mutant Is Delayed for Conidium Germination and Pathogenesis in Magnaporthe oryzae. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1096913
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096913