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Health-Related Quality of Life in Children and Adolescents with Hereditary Bleeding Disorders and in Children and Adolescents with Stroke: Cross-Sectional Comparison to Siblings and Peers
Joint Authors
Holzhauer, Susanne
Kurnik, Karin
Nowak-Göttl, Ulrike
Neuner, Bruno
von Mackensen, Sylvia
Funk, Stephanie
Klamroth, Robert
Krümpel, Anne
Halimeh, Susan
Reinke, Sarah
Frühwald, Michael
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
To investigate self-reported health-related quality of life (HrQoL) in children and adolescents with chronic medical conditions compared with siblings/peers.
Methods.
Group 1 (6 treatment centers) consisted of 74 children/adolescents aged 8–16 years with hereditary bleeding disorders (HBD), 12 siblings, and 34 peers.
Group 2 (one treatment center) consisted of 70 children/adolescents with stroke/transient ischemic attack, 14 siblings, and 72 peers.
HrQoL was assessed with the “revised KINDer Lebensqualitätsfragebogen” (KINDL-R) questionnaire.
Multivariate analyses within groups were done by one-way ANOVA and post hoc pairwise single comparisons by Student’s t -tests.
Adjusted pairwise comparisons were done by hierarchical linear regressions with individuals nested within treatment centers (group 1) and by linear regressions (group 2), respectively.
Results.
No differences were found in multivariate analyses of self-reported HrQoL in group 1, while in group 2 differences occurred in overall wellbeing and all subdimensions.
These differences were due to differences between patients and peers.
After adjusting for age, gender, number of siblings, and treatment center these differences persisted regarding self-worth ( p = .
0040 ) and friend-related wellbeing ( p < .
001 ).
Conclusions.
In children with HBD, HrQoL was comparable to siblings and peers.
In children with stroke/TIA HrQoL was comparable to siblings while peers, independently of relevant confounder, showed better self-worth and friend-related wellbeing.
American Psychological Association (APA)
Neuner, Bruno& von Mackensen, Sylvia& Holzhauer, Susanne& Funk, Stephanie& Klamroth, Robert& Kurnik, Karin…[et al.]. 2016. Health-Related Quality of Life in Children and Adolescents with Hereditary Bleeding Disorders and in Children and Adolescents with Stroke: Cross-Sectional Comparison to Siblings and Peers. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1096914
Modern Language Association (MLA)
Neuner, Bruno…[et al.]. Health-Related Quality of Life in Children and Adolescents with Hereditary Bleeding Disorders and in Children and Adolescents with Stroke: Cross-Sectional Comparison to Siblings and Peers. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1096914
American Medical Association (AMA)
Neuner, Bruno& von Mackensen, Sylvia& Holzhauer, Susanne& Funk, Stephanie& Klamroth, Robert& Kurnik, Karin…[et al.]. Health-Related Quality of Life in Children and Adolescents with Hereditary Bleeding Disorders and in Children and Adolescents with Stroke: Cross-Sectional Comparison to Siblings and Peers. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1096914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096914