Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study
Joint Authors
Lane, Kevin
Birkholz, Detlef
Genuis, Stephen J.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Many individuals have been exposed to organochlorinated pesticides (OCPs) through food, water, air, dermal exposure, and/or vertical transmission.
Due to enterohepatic reabsorption and affinity to adipose tissue, OCPs are not efficiently eliminated from the human body and may accrue in tissues.
Many epidemiological studies demonstrate significant exposure-disease relationships suggesting OCPs can alter metabolic function and potentially lead to illness.
There is limited study of interventions to facilitate OCP elimination from the human body.
This study explored the efficacy of induced perspiration as a means to eliminate OCPs.
Methods.
Blood, urine, and sweat (BUS) were collected from 20 individuals.
Analysis of 23 OCPs was performed using dual-column gas chromatography with electron-capture detectors.
Results.
Various OCPs and metabolites, including DDT, DDE, methoxychlor, endrin, and endosulfan sulfate, were excreted into perspiration.
Generally, sweat samples showed more frequent OCP detection than serum or urine analysis.
Many OCPs were not readily detected in blood testing while still being excreted and identified in sweat.
No direct correlation was found among OCP concentrations in the blood, urine, or sweat compartments.
Conclusions.
Sweat analysis may be useful in detecting some accrued OCPs not found in regular serum testing.
Induced perspiration may be a viable clinical tool for eliminating some OCPs.
American Psychological Association (APA)
Genuis, Stephen J.& Lane, Kevin& Birkholz, Detlef. 2016. Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1096921
Modern Language Association (MLA)
Genuis, Stephen J.…[et al.]. Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1096921
American Medical Association (AMA)
Genuis, Stephen J.& Lane, Kevin& Birkholz, Detlef. Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1096921
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096921