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Quantitative Myocardial Perfusion with Dynamic Contrast-Enhanced Imaging in MRI and CT: Theoretical Models and Current Implementation
Joint Authors
Sijens, Paul E.
Slart, Riemer H. J. A.
Pelgrim, Gert Jan
Handayani, Astri
Oudkerk, Matthijs
Vliegenthart, Rozemarijn
Prakken, N.
Dijkstra, H.
Van Ooijen, Peter M.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-10
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Technological advances in magnetic resonance imaging (MRI) and computed tomography (CT), including higher spatial and temporal resolution, have made the prospect of performing absolute myocardial perfusion quantification possible, previously only achievable with positron emission tomography (PET).
This could facilitate integration of myocardial perfusion biomarkers into the current workup for coronary artery disease (CAD), as MRI and CT systems are more widely available than PET scanners.
Cardiac PET scanning remains expensive and is restricted by the requirement of a nearby cyclotron.
Clinical evidence is needed to demonstrate that MRI and CT have similar accuracy for myocardial perfusion quantification as PET.
However, lack of standardization of acquisition protocols and tracer kinetic model selection complicates comparison between different studies and modalities.
The aim of this overview is to provide insight into the different tracer kinetic models for quantitative myocardial perfusion analysis and to address typical implementation issues in MRI and CT.
We compare different models based on their theoretical derivations and present the respective consequences for MRI and CT acquisition parameters, highlighting the interplay between tracer kinetic modeling and acquisition settings.
American Psychological Association (APA)
Pelgrim, Gert Jan& Handayani, Astri& Dijkstra, H.& Prakken, N.& Slart, Riemer H. J. A.& Oudkerk, Matthijs…[et al.]. 2016. Quantitative Myocardial Perfusion with Dynamic Contrast-Enhanced Imaging in MRI and CT: Theoretical Models and Current Implementation. BioMed Research International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1096951
Modern Language Association (MLA)
Pelgrim, Gert Jan…[et al.]. Quantitative Myocardial Perfusion with Dynamic Contrast-Enhanced Imaging in MRI and CT: Theoretical Models and Current Implementation. BioMed Research International No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1096951
American Medical Association (AMA)
Pelgrim, Gert Jan& Handayani, Astri& Dijkstra, H.& Prakken, N.& Slart, Riemer H. J. A.& Oudkerk, Matthijs…[et al.]. Quantitative Myocardial Perfusion with Dynamic Contrast-Enhanced Imaging in MRI and CT: Theoretical Models and Current Implementation. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1096951
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096951