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Predominance of Abdominal Visceral Adipose Tissue Reflects the Presence of Aortic Valve Calcification
Joint Authors
Nakazato, Kazuhiko
Misaka, Tomofumi
Suzuki, Hitoshi
Takeishi, Yasuchika
Oikawa, Masayoshi
Owada, Takashi
Yamauchi, Hiroyuki
Machii, Hirofumi
Saitoh, Shu-ichi
Sugimoto, Koichi
Yamaki, Takayoshi
Kunii, Hiroyuki
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Aortic valve calcification (AVC) is a common feature of aging and is related to coronary artery disease.
Although abdominal visceral adipose tissue (VAT) plays fundamental roles in coronary artery disease, the relationship between abdominal VAT and AVC is not fully understood.
Methods.
We investigated 259 patients who underwent cardiac and abdominal computed tomography (CT).
AVC was defined as calcified lesion on the aortic valve by CT.
%abdominal VAT was calculated as abdominal VAT area/total adipose tissue area.
Results.
AVC was detected in 75 patients, and these patients showed higher %abdominal VAT (44% versus 38%, p<0.05) compared to those without AVC.
When the cutoff value of %abdominal VAT was set at 40.9%, the area under the curve to diagnose AVC was 0.626.
Multivariable logistic regression analysis showed that age (OR 1.120, 95% CI 1.078–1.168, p<0.01), diabetes (OR 2.587, 95% CI 1.323–5.130, p<0.01), and %abdominal VAT (OR 1.032, 95% CI 1.003–1.065, p<0.05) were independent risk factors for AVC.
The net reclassification improvement value for detecting AVC was increased when %abdominal VAT was added to the model: 0.5093 (95% CI 0.2489–0.7697, p<0.01).
Conclusion.
We determined that predominance of VAT is associated with AVC.
American Psychological Association (APA)
Oikawa, Masayoshi& Owada, Takashi& Yamauchi, Hiroyuki& Misaka, Tomofumi& Machii, Hirofumi& Yamaki, Takayoshi…[et al.]. 2016. Predominance of Abdominal Visceral Adipose Tissue Reflects the Presence of Aortic Valve Calcification. BioMed Research International،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1097049
Modern Language Association (MLA)
Oikawa, Masayoshi…[et al.]. Predominance of Abdominal Visceral Adipose Tissue Reflects the Presence of Aortic Valve Calcification. BioMed Research International No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1097049
American Medical Association (AMA)
Oikawa, Masayoshi& Owada, Takashi& Yamauchi, Hiroyuki& Misaka, Tomofumi& Machii, Hirofumi& Yamaki, Takayoshi…[et al.]. Predominance of Abdominal Visceral Adipose Tissue Reflects the Presence of Aortic Valve Calcification. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1097049
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097049