The Role of Targeted Temperature Management in Adult Patients Resuscitated from Nonshockable Cardiac Arrests: An Updated Systematic Review and Meta-Analysis
Joint Authors
Li, Yongqin
Song, Lijuan
Lu, Yubao
Zhang, Lei
Wei, Liang
Wang, Kaifa
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Routine targeted temperature management is recommended for comatose adult patients with return of spontaneous circulation after cardiac arrest.
However, the role of targeted temperature management in patients resuscitated from nonshockable cardiac arrests remains uncertain.
We conducted an updated systematic review and meta-analysis to evaluate the effects of targeted temperature management in this population.
Medline, EMBASE, and Cochrane databases were systematically reviewed for studies published between January 2005 and March 2016, in which targeted temperature management was compared with standard care or normothermia for adult patients resuscitated from nonshockable cardiac arrests.
A total of 25 trials that included 5715 patients were identified from 10985 relevant papers.
Pooled data showed that targeted temperature management not only associated with improved short-term survival (RR = 1.42, 95% CI: 1.28–1.57) and neurological function (RR = 1.63, 95% CI: 1.39–1.91) but also associated with improved long-term survival (RR = 1.64, 95% CI: 1.27–2.12) and neurological recovery (RR = 1.42, 95% CI: 1.07–1.90) in observational cohort studies.
However, more frequent infectious complications were reported in hypothermia-treated patients (RR = 1.46, 95% CI: 1.26–1.70) and the quality of the evidence ranged from moderate to very low.
American Psychological Association (APA)
Song, Lijuan& Wei, Liang& Zhang, Lei& Lu, Yubao& Wang, Kaifa& Li, Yongqin. 2016. The Role of Targeted Temperature Management in Adult Patients Resuscitated from Nonshockable Cardiac Arrests: An Updated Systematic Review and Meta-Analysis. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1097056
Modern Language Association (MLA)
Song, Lijuan…[et al.]. The Role of Targeted Temperature Management in Adult Patients Resuscitated from Nonshockable Cardiac Arrests: An Updated Systematic Review and Meta-Analysis. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1097056
American Medical Association (AMA)
Song, Lijuan& Wei, Liang& Zhang, Lei& Lu, Yubao& Wang, Kaifa& Li, Yongqin. The Role of Targeted Temperature Management in Adult Patients Resuscitated from Nonshockable Cardiac Arrests: An Updated Systematic Review and Meta-Analysis. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1097056
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097056