Pressure Drop in TortuosityKinking of the Internal Carotid Artery: Simulation and Clinical Investigation
Joint Authors
Zhao, Feng
Wang, Lijun
Wang, Daming
Hu, Shen
Liu, Jiachun
Zhou, Zhilun
Lu, Jun
Qi, Peng
Song, Shiying
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Whether carotid tortuosity/kinking of the internal carotid artery leads to cerebral ischemia remains unclear.
There is very little research about the hemodynamic variation induced by carotid tortuosity/kinking in the literature.
The objective of this study was to research the blood pressure changes induced by carotid tortuosity/kinking.
Methods.
We first created a geometric model of carotid tortuosity/kinking.
Based on hemodynamic boundary conditions, the hemodynamics of carotid tortuosity and kinking were studied via a finite element simulation.
Then, an in vitro system was built to validate the numerical simulation results.
The mean arterial pressure changes before and after carotid kinking were measured using pressure sensors in 12 patients with carotid kinking.
Results.
Numerical simulation revealed that the pressure drops increased with increases in the kinking angles.
Clinical tests and in vitro experiments confirmed the numerical simulation results.
Conclusions.
Carotid kinking leads to blood pressure reduction.
In certain conditions, kinking may affect the cerebral blood supply and be associated with cerebral ischemia.
American Psychological Association (APA)
Wang, Lijun& Zhao, Feng& Wang, Daming& Hu, Shen& Liu, Jiachun& Zhou, Zhilun…[et al.]. 2016. Pressure Drop in TortuosityKinking of the Internal Carotid Artery: Simulation and Clinical Investigation. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1097070
Modern Language Association (MLA)
Wang, Lijun…[et al.]. Pressure Drop in TortuosityKinking of the Internal Carotid Artery: Simulation and Clinical Investigation. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1097070
American Medical Association (AMA)
Wang, Lijun& Zhao, Feng& Wang, Daming& Hu, Shen& Liu, Jiachun& Zhou, Zhilun…[et al.]. Pressure Drop in TortuosityKinking of the Internal Carotid Artery: Simulation and Clinical Investigation. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1097070
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097070