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Recent Advances in Treatments of Primary Focal Segmental Glomerulosclerosis in Children
Joint Authors
Han, Kyoung Hee
Kim, Seong Heon
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Focal segmental glomerulosclerosis (FSGS) is a nephrotic syndrome.
Up to around 80% of cases of primary FSGS are resistant to steroid treatment.
A large proportion of patients with steroid-resistant FSGS progress to end-stage renal disease.
The purpose of treatment is to obtain a complete remission of proteinuria, a necessary step that precedes improved renal survival and reduces the risk of progression to chronic kidney disease.
When this is not possible, the secondary goal is a partial remission of proteinuria.
Reduction or remission of proteinuria is the most important factor predictive of renal survival.
We will review the current updated strategies for treatment of primary FSGS in children, including traditional therapies consisting of corticosteroids and calcineurin inhibitors and novel therapies such as rituximab, abatacept, adalimumab, and fresolimumab.
American Psychological Association (APA)
Han, Kyoung Hee& Kim, Seong Heon. 2016. Recent Advances in Treatments of Primary Focal Segmental Glomerulosclerosis in Children. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097217
Modern Language Association (MLA)
Han, Kyoung Hee& Kim, Seong Heon. Recent Advances in Treatments of Primary Focal Segmental Glomerulosclerosis in Children. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097217
American Medical Association (AMA)
Han, Kyoung Hee& Kim, Seong Heon. Recent Advances in Treatments of Primary Focal Segmental Glomerulosclerosis in Children. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097217
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097217