Clinical Distinctness of Allergic Rhinitis in Patients with Allergy to Molds
Joint Authors
Kołodziejczyk, Krzysztof
Bozek, Andrzej
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Molds are a very diverse group of allergens.
Exposure and sensitization to fungal allergens can promote the development and worsening of allergic rhinitis (AR).
Objective.
The natural course of allergic rhinitis was compared between a group of patients with allergy to molds and patients with AR to other allergens as the control groups.
Material and Methods.
The study group consisted of 229 patients, with a mean age of 27.4 ± 6.5 yrs.
The study group was compared to groups of AR patients with allergy to house dust mites or pollens or with multivalent allergy.
Allergic sensitization was assessed using the skin prick test (SPT) with a panel of 15 allergens to molds and other common inhalant allergens.
Specific IgEs against all tested allergens were measured.
Nasal fractional exhaled nitric oxide (FeNO) level was assessed with a chemiluminescence analyzer (NIOX MINO) and compared between groups.
Cluster analysis was performed for determine models of AR in whole population.
Results.
Patients with allergy to mold have had AR with a higher blockage of nose than in the patients with other allergies.
Alternaria alternata (59% of examined), Cladosporium herbarum (40%), and Aspergillus fumigatus (36%) were the predominant allergens in the study group.
Patients with allergy to mold were more often present in two clusters: there were patients with more frequent accompanying asthma and high level of FeNO.
Conclusion.
Patients with allergy to molds have a significantly greater predisposition for bronchial asthma and high concentration of FeNO.
American Psychological Association (APA)
Kołodziejczyk, Krzysztof& Bozek, Andrzej. 2016. Clinical Distinctness of Allergic Rhinitis in Patients with Allergy to Molds. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097245
Modern Language Association (MLA)
Kołodziejczyk, Krzysztof& Bozek, Andrzej. Clinical Distinctness of Allergic Rhinitis in Patients with Allergy to Molds. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097245
American Medical Association (AMA)
Kołodziejczyk, Krzysztof& Bozek, Andrzej. Clinical Distinctness of Allergic Rhinitis in Patients with Allergy to Molds. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097245
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097245