The association of human cytomegalovirus infection of male genital tract and male infertility
Other Title(s)
العلاقة بين الفيروسات المضخمه للخلايا التي تصيب القناة التناسلية عند الرجال مع الذكور العقيمين
Joint Authors
Abd al-Amir, Ahmad Sahib
Hasan, Salah Mahdi
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 26, Issue 10 (31 Dec. 2018), pp.51-57, 7 p.
Publisher
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
Background: The human cytomegalovirus (HCMV) is a widely distributed virus among humans and is included within the sexually transmitted viruses.
Because its low detection rate in semen, the impact of HCMV on sperm formation and its vertical transmission within the sperm cells has not been studied sufficiently.
Objectives: To investigate the association of viral infections present in the lower genital tract of males and relationship among males infertility.
Methods: ELISA and RT-PCR technique of 100 semen and serum specimens, collected over 8 months from males investigated for infertility, were retrospectively assessed, by screening anti-human Herpes Simplex Virus (HCMV) IgM and IgG in the serum and detection of HSV DNA in seminal fluid.
Results: One hundred seminal fluid and blood samples were taken from men and investigated for infertility over a period of 8 months from July 2016 to February 2017.
The seminal fluids and serum of patients mentioned to the laboratory from the fertility clinics of Kamal AL-samarai hospital and outer clinics.
The investigations were conducted to find the HCMV detection rate in the seminal fluid of infertile men and to evaluate the impact of the viral infection on the major sperm parameters.
Blood and seminal fluid were collected from 100 infertile males.
The results were shown that 24/100 (24.0%) were positive for IgM and 86/100 (86.0%) were positive for IgG of HCMV.
In case of control group, results were (1.0%) positive for anti-HCMV IgM antibodies, while (20.0%) positive for anti-HCMV IgG antibodies in control group, using ELISA test.
The PCR showed that out of 100 samples 24 (24.0%) gave positive results for HCMV patients, while 7 (7.0%) positive for HCMV in control group.
Conclusions: Using sensitive procedures for assays, seminal samples of asymptomatic infertile patients showed unexpectedly high incidence of the sexually transmitted pathogens.
American Psychological Association (APA)
Abd al-Amir, Ahmad Sahib& Hasan, Salah Mahdi. 2018. The association of human cytomegalovirus infection of male genital tract and male infertility. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 26, no. 10, pp.51-57.
https://search.emarefa.net/detail/BIM-1097277
Modern Language Association (MLA)
Abd al-Amir, Ahmad Sahib& Hasan, Salah Mahdi. The association of human cytomegalovirus infection of male genital tract and male infertility. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 26, no. 10 (2018), pp.51-57.
https://search.emarefa.net/detail/BIM-1097277
American Medical Association (AMA)
Abd al-Amir, Ahmad Sahib& Hasan, Salah Mahdi. The association of human cytomegalovirus infection of male genital tract and male infertility. Journal of Babylon University : Journal of Applied and Pure Sciences. 2018. Vol. 26, no. 10, pp.51-57.
https://search.emarefa.net/detail/BIM-1097277
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-1097277