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Antidermatophytic Activity of Ethanolic Extract from Croton tiglium
Joint Authors
Kuo, Yu-Liang
Lin, Han Chien
Lee, Wen-Ju
Yap, Hui-Yi
Wang, Shao-Hung
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Dermatophytosis, which is caused mainly by genera of Trichophyton, Epidermophyton, and Microsporum, is a frequent dermatological problem in tropical and subtropical countries.
Investigations were carried out in this study to evaluate the antidermatophytic activity of the stems, leaves, and seeds of Croton tiglium, one of the traditional medicine plants indigenous to Asia.
Ethanolic extracts of the stems, leaves, and seeds of C.
tiglium were prepared by cold soak or heat reflux methods.
The antidermatophytic activities of the extracts were evaluated by disc diffusion and microdilution susceptibility assays against Trichophyton mentagrophytes, T.
rubrum, and Epidermophyton floccosum.
The active components in the extracts were analyzed and identified by GC-MS.
All ethanolic extracts of C.
tiglium showed some antifungal activities against the three dermatophytes.
The ethanolic stem extract had the greatest inhibitory activities against T.
mentagrophytes and E.
floccosum with MICs at 0.16 mg/mL and had a lower activity against T.
rubrum (MIC: 0.31 mg/mL).
Oleic acid and hexadecanoic acid were found to be the major constituents in the stem extract that demonstrated strong antidermatophytic activities.
The ethanolic extracts of stem or seed of C.
tiglium exhibit strong antidermatophytic activities and, thus, could be considered for application on treating skin fungal infections after appropriate processing.
American Psychological Association (APA)
Lin, Han Chien& Kuo, Yu-Liang& Lee, Wen-Ju& Yap, Hui-Yi& Wang, Shao-Hung. 2016. Antidermatophytic Activity of Ethanolic Extract from Croton tiglium. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097307
Modern Language Association (MLA)
Lin, Han Chien…[et al.]. Antidermatophytic Activity of Ethanolic Extract from Croton tiglium. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097307
American Medical Association (AMA)
Lin, Han Chien& Kuo, Yu-Liang& Lee, Wen-Ju& Yap, Hui-Yi& Wang, Shao-Hung. Antidermatophytic Activity of Ethanolic Extract from Croton tiglium. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097307
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097307