No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL1223
Joint Authors
Lin, Shang-Hung
Ho, Ji-Chen
Lee, Chih-Hung
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Psoriasis is associated with atherosclerosis, in which circulating microparticles play an important role.
In severe psoriasis, there was an increase of endothelial- and platelet- microparticles which could be decreased by anti-TNFα.
However, whether anti-IL-12/23 treatment would decrease the level of microparticles remains unknown.
Our study showed that, despite the clinical improvement of psoriasis after IL-12/13 blockage, the increased levels of circulating CD41a and CD31 microparticles were unchanged after anti-IL-12/23.
This result suggested that anti-IL12/23 treatment may not alter the development of cardiovascular disease in patients with psoriasis.
American Psychological Association (APA)
Ho, Ji-Chen& Lee, Chih-Hung& Lin, Shang-Hung. 2016. No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL1223. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097311
Modern Language Association (MLA)
Ho, Ji-Chen…[et al.]. No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL1223. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097311
American Medical Association (AMA)
Ho, Ji-Chen& Lee, Chih-Hung& Lin, Shang-Hung. No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL1223. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097311