Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes
Joint Authors
Turkmen, Kultigin
Onk, Didem
Akarsu Ayazoğlu, Tülin
Onk, Oruç Alper
Aksüt, Mehmet
Günay, Murat
Özensoy, Aynur
Yazıcı Ersoy, Çiğdem
Çoban, Abdulkadir
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Increased levels of stress hormones are associated with mortality in patients undergoing coronary artery bypass grafting (CABG).
Aim.
To compare total intravenous anaesthesia (TIVA) and desflurane added to a subanaesthetic dose of propofol.
Material and Methods.
Fifty patients were enrolled in this study.
Fentanyl (3–5 mcg/kg/h) was started in both groups.
Patients were divided into two groups.
The PD group ( n = 2 5 ) received 1 minimum alveolar concentration (MAC) desflurane anaesthesia in addition to propofol infusion (2-3 mg/kg/h), while P group ( n = 2 5 ) received propofol infusion (5-6 mg/kg/h) only.
Biochemical data, cortisol, and insulin levels were measured preoperatively (T0), after initiation of CPB but before cross-clamping the aorta (T1), after removal of the cross-clamp (T2), and at the 24th postoperative hour (T3).
Results.
Systolic, diastolic, and mean arterial pressure levels were significantly higher in PD group than those in P group in T1 and T2 measurements ( p ≤ 0.05 ).
CK-MB showed a significant decrease in group P ( p ≤ 0.05 ).
When we compared both groups, cortisol levels were significantly higher in PD group than P group ( p ≤ 0.05 ).
Conclusion.
Stress and haemodynamic responses were better controlled using TIVA than desflurane inhalation added to a subanaesthetic dose of propofol in patients undergoing CABG.
American Psychological Association (APA)
Onk, Didem& Akarsu Ayazoğlu, Tülin& Onk, Oruç Alper& Aksüt, Mehmet& Günay, Murat& Turkmen, Kultigin…[et al.]. 2016. Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097322
Modern Language Association (MLA)
Onk, Didem…[et al.]. Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097322
American Medical Association (AMA)
Onk, Didem& Akarsu Ayazoğlu, Tülin& Onk, Oruç Alper& Aksüt, Mehmet& Günay, Murat& Turkmen, Kultigin…[et al.]. Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097322
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097322