![](/images/graphics-bg.png)
Role of Membrane Lipids in the Regulation of Erythrocytic Oxygen-Transport Function in Cardiovascular Diseases
Joint Authors
Gromova, Natalia V.
Solomadin, Ilia N.
Tychkov, Alexander Yu.
Revina, Elvira S.
Martynova, Maria I.
Seikina, Angelina I.
Revina, Nadezhda V.
Imarova, Oksana G.
Zhelev, Nikolai
Revin, Victor V.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-30
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The composition and condition of membrane lipids, the morphology of erythrocytes, and hemoglobin distribution were explored with the help of laser interference microscopy (LIM) and Raman spectroscopy.
It is shown that patients with cardiovascular diseases (CVD) have significant changes in the composition of their phospholipids and the fatty acids of membrane lipids.
Furthermore, the microviscosity of the membranes and morphology of the erythrocytes are altered causing disordered oxygen transport by hemoglobin.
Basic therapy carried out with the use of antiaggregants, statins, antianginals, beta-blockers, and calcium antagonists does not help to recover the morphofunctional properties of erythrocytes.
Based on the results the authors assume that, for the relief of the ischemic crisis and further therapeutic treatment, it is necessary to include, in addition to cardiovascular disease medicines, medication that increases the ability of erythrocytes’ hemoglobin to transport oxygen to the tissues.
We assume that the use of LIM and Raman spectroscopy is advisable for early diagnosis of changes in the structure and functional state of erythrocytes when cardiovascular diseases develop.
American Psychological Association (APA)
Revin, Victor V.& Gromova, Natalia V.& Revina, Elvira S.& Martynova, Maria I.& Seikina, Angelina I.& Revina, Nadezhda V.…[et al.]. 2016. Role of Membrane Lipids in the Regulation of Erythrocytic Oxygen-Transport Function in Cardiovascular Diseases. BioMed Research International،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1097342
Modern Language Association (MLA)
Revin, Victor V.…[et al.]. Role of Membrane Lipids in the Regulation of Erythrocytic Oxygen-Transport Function in Cardiovascular Diseases. BioMed Research International No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1097342
American Medical Association (AMA)
Revin, Victor V.& Gromova, Natalia V.& Revina, Elvira S.& Martynova, Maria I.& Seikina, Angelina I.& Revina, Nadezhda V.…[et al.]. Role of Membrane Lipids in the Regulation of Erythrocytic Oxygen-Transport Function in Cardiovascular Diseases. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1097342
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097342