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Patterning of Endothelial Cells and Mesenchymal Stem Cells by Laser-Assisted Bioprinting to Study Cell Migration
Joint Authors
Bourget, Jean-Michel
Remy, Murielle
Kérourédan, Olivia
Medina, Manuela
Thébaud, Noélie Brunehilde
Bareille, Reine
Chassande, Olivier
Amédée, Joëlle
Catros, Sylvain
Devillard, Raphaël
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tissue engineering of large organs is currently limited by the lack of potent vascularization in vitro.
Tissue-engineered bone grafts can be prevascularized in vitro using endothelial cells (ECs).
The microvascular network architecture could be controlled by printing ECs following a specific pattern.
Using laser-assisted bioprinting, we investigated the effect of distance between printed cell islets and the influence of coprinted mesenchymal cells on migration.
When printed alone, ECs spread out evenly on the collagen hydrogel, regardless of the distance between cell islets.
However, when printed in coculture with mesenchymal cells by laser-assisted bioprinting, they remained in the printed area.
Therefore, the presence of mesenchymal cell is mandatory in order to create a pattern that will be conserved over time.
This work describes an interesting approach to study cell migration that could be reproduced to study the effect of trophic factors.
American Psychological Association (APA)
Bourget, Jean-Michel& Kérourédan, Olivia& Medina, Manuela& Remy, Murielle& Thébaud, Noélie Brunehilde& Bareille, Reine…[et al.]. 2016. Patterning of Endothelial Cells and Mesenchymal Stem Cells by Laser-Assisted Bioprinting to Study Cell Migration. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097366
Modern Language Association (MLA)
Bourget, Jean-Michel…[et al.]. Patterning of Endothelial Cells and Mesenchymal Stem Cells by Laser-Assisted Bioprinting to Study Cell Migration. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1097366
American Medical Association (AMA)
Bourget, Jean-Michel& Kérourédan, Olivia& Medina, Manuela& Remy, Murielle& Thébaud, Noélie Brunehilde& Bareille, Reine…[et al.]. Patterning of Endothelial Cells and Mesenchymal Stem Cells by Laser-Assisted Bioprinting to Study Cell Migration. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097366
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097366