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Comprehensive Evaluation of Personal, Clinical, and Radiation Dosimetric Parameters for Acute Skin Reaction during Whole Breast Radiotherapy
Joint Authors
Lee, Jung Ae
Kim, Chul Yong
Yang, Dae Sik
Yoon, Won Sup
Park, Young Je
Lee, Suk
Lee, Nam Kwon
Son, Gil Soo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Skin reaction is major problem during whole breast radiotherapy.
To identify factors related to skin reactions during whole breast radiotherapy, various personal, clinical, and radiation dosimetric parameters were evaluated.
From January 2012 to December 2013, a total of 125 patients who underwent breast conserving surgery and adjuvant whole breast irradiation were retrospectively reviewed.
All patients had both whole breast irradiation and boost to the tumour bed.
Skin reaction was measured on the first day of boost therapy based on photography of the radiation field and medical records.
For each area of axilla and inferior fold, the intensity score of erythema (score 1 to 5) and extent (score 0 to 1) were summed.
The relationship of various parameters to skin reaction was evaluated using chi-square and linear regression tests.
The V 100 (volume receiving 100% of prescribed radiation dose, p < 0.001 , both axilla and inferior fold) and age ( p = 0.039 for axilla and 0.026 for inferior fold) were significant parameters in multivariate analyses.
The calculated axilla dose ( p = 0.003 ) and breast separation ( p = 0.036 ) were also risk factors for axilla and inferior fold, respectively.
Young age and large V 100 are significant factors for acute skin reaction that can be simply and cost-effectively measured.
American Psychological Association (APA)
Yang, Dae Sik& Lee, Jung Ae& Yoon, Won Sup& Lee, Nam Kwon& Park, Young Je& Lee, Suk…[et al.]. 2016. Comprehensive Evaluation of Personal, Clinical, and Radiation Dosimetric Parameters for Acute Skin Reaction during Whole Breast Radiotherapy. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097398
Modern Language Association (MLA)
Yang, Dae Sik…[et al.]. Comprehensive Evaluation of Personal, Clinical, and Radiation Dosimetric Parameters for Acute Skin Reaction during Whole Breast Radiotherapy. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1097398
American Medical Association (AMA)
Yang, Dae Sik& Lee, Jung Ae& Yoon, Won Sup& Lee, Nam Kwon& Park, Young Je& Lee, Suk…[et al.]. Comprehensive Evaluation of Personal, Clinical, and Radiation Dosimetric Parameters for Acute Skin Reaction during Whole Breast Radiotherapy. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097398