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Paramagnetic Manganese in the Atherosclerotic Plaque of Carotid Arteries
Joint Authors
Chelyshev, Yury
Gafurov, Marat
Ignatyev, Igor
Zanochkin, Alexey
Mamin, Georgy
Sorokin, Boris
Sorokina, Alexandra
Lyapkalo, Natalya
Gizatullina, Nazima
Mukhamedshina, Yana
Orlinskii, Sergei
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The search for adequate markers of atherosclerotic plaque (AP) instability in the context of assessment of the ischemic stroke risk in patients with atherosclerosis of the carotid arteries as well as for solid physical and chemical factors that are connected with the AP stability is extremely important.
We investigate the inner lining of the carotid artery specimens from the male patients with atherosclerosis (27 patients, 42–64 years old) obtained during carotid endarterectomy by using different analytical tools including ultrasound angiography, X-ray analysis, immunological, histochemical analyses, and high-field (3.4 T) pulse electron paramagnetic resonance (EPR) at 94 GHz.
No correlation between the stable and unstable APs in the sense of the calcification is revealed.
In all of the investigated samples, the EPR spectra of manganese, namely, Mn2+ ions, are registered.
Spectral and relaxation characteristics of Mn2+ ions are close to those obtained for the synthetic (nano) hydroxyapatite species but differ from each other for stable and unstable APs.
This demonstrates that AP stability could be specified by the molecular organization of their hydroxyapatite components.
The origin of the obtained differences and the possibility of using EPR of Mn2+ as an AP stability marker are discussed.
American Psychological Association (APA)
Chelyshev, Yury& Gafurov, Marat& Ignatyev, Igor& Zanochkin, Alexey& Mamin, Georgy& Sorokin, Boris…[et al.]. 2016. Paramagnetic Manganese in the Atherosclerotic Plaque of Carotid Arteries. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097411
Modern Language Association (MLA)
Chelyshev, Yury…[et al.]. Paramagnetic Manganese in the Atherosclerotic Plaque of Carotid Arteries. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1097411
American Medical Association (AMA)
Chelyshev, Yury& Gafurov, Marat& Ignatyev, Igor& Zanochkin, Alexey& Mamin, Georgy& Sorokin, Boris…[et al.]. Paramagnetic Manganese in the Atherosclerotic Plaque of Carotid Arteries. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097411
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097411