![](/images/graphics-bg.png)
Partially Purified Extracts of Sea Anemone Anemonia viridis Affect the Growth and Viability of Selected Tumour Cell Lines
Joint Authors
Colombo, Paolo
Nicosia, Aldo
Salamone, Monica
Mazzola, Salvatore
Cuttitta, Angela
Bulati, Matteo
Longo, Alessandra
Masullo, Tiziana
Vlah, Sara
Bennici, Carmelo
Bonura, Angela
Tagliavia, Marcello
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
In the last few years, marine species have been investigated for the presence of natural products with anticancer activity.
Using reversed phase chromatography, low molecular weight proteins were fractionated from the sea anemone Anemonia viridis.
Four different fractions were evaluated for their cytotoxic activity by means of erythrocyte haemolysis test, MTS, and LDH assays.
Finally, the antiproliferative activities of three of these fractions were studied on PC3, PLC/PRF/5, and A375 human cancer cell lines.
Our analysis revealed that the four fractions showed different protein contents and diverse patterns of activity towards human PBMC and cancer cell lines.
Interestingly, fractions III and IV exerted cytotoxic effects on human cells.
Conversely, fractions I and II displayed very low toxic effects associated with antiproliferative activities on cancer cell lines.
American Psychological Association (APA)
Bulati, Matteo& Longo, Alessandra& Masullo, Tiziana& Vlah, Sara& Bennici, Carmelo& Bonura, Angela…[et al.]. 2016. Partially Purified Extracts of Sea Anemone Anemonia viridis Affect the Growth and Viability of Selected Tumour Cell Lines. BioMed Research International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1097477
Modern Language Association (MLA)
Bulati, Matteo…[et al.]. Partially Purified Extracts of Sea Anemone Anemonia viridis Affect the Growth and Viability of Selected Tumour Cell Lines. BioMed Research International No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1097477
American Medical Association (AMA)
Bulati, Matteo& Longo, Alessandra& Masullo, Tiziana& Vlah, Sara& Bennici, Carmelo& Bonura, Angela…[et al.]. Partially Purified Extracts of Sea Anemone Anemonia viridis Affect the Growth and Viability of Selected Tumour Cell Lines. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1097477
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097477