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Approaches to Peripheral Nerve Repair: Generations of Biomaterial Conduits Yielding to Replacing Autologous Nerve Grafts in Craniomaxillofacial Surgery
Joint Authors
Gaudin, Robert
Knipfer, Christian
Henningsen, Anders
Hadlock, Tessa
Smeets, Ralf
Heiland, Max
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Peripheral nerve injury is a common clinical entity, which may arise due to traumatic, tumorous, or even iatrogenic injury in craniomaxillofacial surgery.
Despite advances in biomaterials and techniques over the past several decades, reconstruction of nerve gaps remains a challenge.
Autografts are the gold standard for nerve reconstruction.
Using autografts, there is donor site morbidity, subsequent sensory deficit, and potential for neuroma development and infection.
Moreover, the need for a second surgical site and limited availability of donor nerves remain a challenge.
Thus, increasing efforts have been directed to develop artificial nerve guidance conduits (ANCs) as new methods to replace autografts in the future.
Various synthetic conduit materials have been tested in vitro and in vivo, and several first- and second-generation conduits are FDA approved and available for purchase, while third-generation conduits still remain in experimental stages.
This paper reviews the current treatment options, summarizes the published literature, and assesses future prospects for the repair of peripheral nerve injury in craniomaxillofacial surgery with a particular focus on facial nerve regeneration.
American Psychological Association (APA)
Gaudin, Robert& Knipfer, Christian& Henningsen, Anders& Smeets, Ralf& Heiland, Max& Hadlock, Tessa. 2016. Approaches to Peripheral Nerve Repair: Generations of Biomaterial Conduits Yielding to Replacing Autologous Nerve Grafts in Craniomaxillofacial Surgery. BioMed Research International،Vol. 2016, no. 2016, pp.1-18.
https://search.emarefa.net/detail/BIM-1097481
Modern Language Association (MLA)
Gaudin, Robert…[et al.]. Approaches to Peripheral Nerve Repair: Generations of Biomaterial Conduits Yielding to Replacing Autologous Nerve Grafts in Craniomaxillofacial Surgery. BioMed Research International No. 2016 (2016), pp.1-18.
https://search.emarefa.net/detail/BIM-1097481
American Medical Association (AMA)
Gaudin, Robert& Knipfer, Christian& Henningsen, Anders& Smeets, Ralf& Heiland, Max& Hadlock, Tessa. Approaches to Peripheral Nerve Repair: Generations of Biomaterial Conduits Yielding to Replacing Autologous Nerve Grafts in Craniomaxillofacial Surgery. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-18.
https://search.emarefa.net/detail/BIM-1097481
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097481