Mechanoregulation of Wound Healing and Skin Homeostasis
Joint Authors
Taradaj, Jakub
Rosińczuk, Joanna
Sopel, Mirosław
Dymarek, Robert
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-20
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Basic and clinical studies on mechanobiology of cells and tissues point to the importance of mechanical forces in the process of skin regeneration and wound healing.
These studies result in the development of new therapies that use mechanical force which supports effective healing.
A better understanding of mechanobiology will make it possible to develop biomaterials with appropriate physical and chemical properties used to treat poorly healing wounds.
In addition, it will make it possible to design devices precisely controlling wound mechanics and to individualize a therapy depending on the type, size, and anatomical location of the wound in specific patients, which will increase the clinical efficiency of the therapy.
Linking mechanobiology with the science of biomaterials and nanotechnology will enable in the near future precise interference in abnormal cell signaling responsible for the proliferation, differentiation, cell death, and restoration of the biological balance.
The objective of this study is to point to the importance of mechanobiology in regeneration of skin damage and wound healing.
The study describes the influence of rigidity of extracellular matrix and special restrictions on cell physiology.
The study also defines how and what mechanical changes influence tissue regeneration and wound healing.
The influence of mechanical signals in the process of proliferation, differentiation, and skin regeneration is tagged in the study.
American Psychological Association (APA)
Rosińczuk, Joanna& Taradaj, Jakub& Dymarek, Robert& Sopel, Mirosław. 2016. Mechanoregulation of Wound Healing and Skin Homeostasis. BioMed Research International،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1097503
Modern Language Association (MLA)
Rosińczuk, Joanna…[et al.]. Mechanoregulation of Wound Healing and Skin Homeostasis. BioMed Research International No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1097503
American Medical Association (AMA)
Rosińczuk, Joanna& Taradaj, Jakub& Dymarek, Robert& Sopel, Mirosław. Mechanoregulation of Wound Healing and Skin Homeostasis. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1097503
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097503