The Time Course of Pulmonary Function Tests in COPD Patients with Different Levels of Blood Eosinophils
Joint Authors
Rogliani, Paola
Puxeddu, Ermanno
Ciaprini, Chiara
Ora, Josuel
Onorato, Angelo
Pezzuto, Gabriella
Calzetta, Luigino
Cazzola, Mario
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Only very few studies have investigated the influence of eosinophils on the functional progression of COPD.
We aimed at retrospectively analyzing the trend of pulmonary function tests over time in patients with COPD according to two baseline blood eosinophil cell count strata (<2% [EOS−] and ≥2% [EOS+]).
We used the last 9-year data present in the database of our outpatient clinic and selected only those who had two blood counts that would guarantee the stability of the value of eosinophils and serial spirometry for 4 consecutive years.
The analysis of the time course of the spirometric variables analysed showed differences in FEV1 and FVC decline between the subjects of the EOS− group and those of the EOS+ group.
The integrated evaluation of our results suggests that the different level of blood eosinophils in the two groups may have influenced independently the time course of the pulmonary function tests and identify two subgroups of subjects with specific disease characteristics: the hyperinflator and the rapid decliner, respectively.
American Psychological Association (APA)
Rogliani, Paola& Puxeddu, Ermanno& Ciaprini, Chiara& Ora, Josuel& Onorato, Angelo& Pezzuto, Gabriella…[et al.]. 2016. The Time Course of Pulmonary Function Tests in COPD Patients with Different Levels of Blood Eosinophils. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097809
Modern Language Association (MLA)
Rogliani, Paola…[et al.]. The Time Course of Pulmonary Function Tests in COPD Patients with Different Levels of Blood Eosinophils. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1097809
American Medical Association (AMA)
Rogliani, Paola& Puxeddu, Ermanno& Ciaprini, Chiara& Ora, Josuel& Onorato, Angelo& Pezzuto, Gabriella…[et al.]. The Time Course of Pulmonary Function Tests in COPD Patients with Different Levels of Blood Eosinophils. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097809
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097809