Prevalence and Prognosis of Anemia in Dogs with Degenerative Mitral Valve Disease
Joint Authors
Yu, Ivarosa Bing-Ye
Huang, Hui-Pi
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
In humans, heart failure (HF) and renal insufficiency (RI) have negative reciprocal effects, and anemia can exacerbate their progression.
In this retrospective study, the prevalence and prognostic significance of anemia in 114 dogs with degenerative mitral valve disease (DMVD) was investigated.
Pretreatment clinical parameters, prevalence of anemia and azotemia, and survival time were analyzed in relation to HF severity.
The prevalence of anemia was highest in dogs with the modified New York Heart Association (NYHA) class IV HF (33.3%), followed by classes III (15.2%) and II (0%; p < 0.001).
The presence of anemia was associated with HF severity and blood creatinine > 1.6 mg/dL (both p < 0.001).
Anemic dogs had a shorter median survival [13 months; 95% confidence interval (CI): 0.7–19.1] than nonanemic dogs (28 months; 95% CI: 15.3–40.7; p < .001).
NYHA class IV (hazard ratio (HR): 3.1, 95% CI: 2.2–4.3; p < 0.001), left atrium/aorta ratio > 1.7 (HR: 2.7, 95% CI: 1.7–4.2; p = 0.001), and presence of anemia (HR: 1.43, 95% CI: 1.1–1.9; p = 0.004) emerged as predictors of mortality.
A cardiorenal-anemia syndrome-like triangle was observed and anemia was a prognostic factor for survival in dogs with DMVD.
American Psychological Association (APA)
Yu, Ivarosa Bing-Ye& Huang, Hui-Pi. 2016. Prevalence and Prognosis of Anemia in Dogs with Degenerative Mitral Valve Disease. BioMed Research International،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1097880
Modern Language Association (MLA)
Yu, Ivarosa Bing-Ye& Huang, Hui-Pi. Prevalence and Prognosis of Anemia in Dogs with Degenerative Mitral Valve Disease. BioMed Research International No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1097880
American Medical Association (AMA)
Yu, Ivarosa Bing-Ye& Huang, Hui-Pi. Prevalence and Prognosis of Anemia in Dogs with Degenerative Mitral Valve Disease. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1097880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097880