The Clinical and Medicolegal Analysis of Electrical Shocked Rats: Based on the Serological and Histological Methods
Joint Authors
Liu, Huitong
Wang, Qiaofeng
Zhao, Ze
Xie, Yanan
Ding, Suzhen
Wang, Zhenyuan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-25
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This research was aimed at discovering the serological and histological changes in cardiac and hepatic tissue after electric shock.
The CK-MB, ALT, and AMS indexes were tested with serological methods.
Moreover, the Bcl-2, Bax, and Hsp-60 expression levels were carefully measured.
An electrical injury model was established by giving rats electric shocks at 110 V with alternating electric current.
Blood samples from the rats were analyzed for the biochemical indexes.
The degrees of pathological changes in the heart and liver were evaluated using IHC staining for Bcl-2, Bax, and Hsp-60.
The levels of CK-MB in the electrical injury group rapidly peaked at 0.5 hours after the electric shock.
Additionally, the levels of Bcl-2, Bax, and Hsp-60 in the cardiac and hepatic tissues changed regularly after the electrical injury and exhibited apparent differences from the levels in the control group.
CK-MB, ALT, and AMS were altered regularly after electric shock, and these results provide significant information for clinical and medicolegal practice.
This research has shed light on the assessment of electrical injury without obvious electrical burns.
Furthermore, the findings obtained for Bcl-2/Bax and Hsp-60 can also facilitate pathological diagnosis and the identification of antemortem and postmortem electrical injury.
American Psychological Association (APA)
Liu, Huitong& Wang, Qiaofeng& Zhao, Ze& Xie, Yanan& Ding, Suzhen& Wang, Zhenyuan. 2016. The Clinical and Medicolegal Analysis of Electrical Shocked Rats: Based on the Serological and Histological Methods. BioMed Research International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1097935
Modern Language Association (MLA)
Liu, Huitong…[et al.]. The Clinical and Medicolegal Analysis of Electrical Shocked Rats: Based on the Serological and Histological Methods. BioMed Research International No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1097935
American Medical Association (AMA)
Liu, Huitong& Wang, Qiaofeng& Zhao, Ze& Xie, Yanan& Ding, Suzhen& Wang, Zhenyuan. The Clinical and Medicolegal Analysis of Electrical Shocked Rats: Based on the Serological and Histological Methods. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1097935
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1097935