Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism
Joint Authors
Teng, Weiping
Han, Cheng
Xia, Xinghai
Liu, Aihua
Zhang, Xiaowen
Zhou, Mi
Xiong, Chuhui
Liu, Xin
Sun, Jie
Shi, Xiaoguang
Shan, Zhongyan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Thyroid hormone (TH) affects many metabolic processes such as promoting oxidation of sugar, fat, and protein in many tissues.
Thyroid dysfunction is associated with metabolic disorders.
The newly discovered adipocyte- and hepatocyte-derived cytokine, betatrophin, has been reported to be involved in metabolic diseases, but its influence on thyroid dysfunction is uncertain.
Therefore, the present study aims to evaluate circulating betatrophin levels in subjects with different thyroid function status and to predict the factors associated with betatrophin levels, especially whether thyroid stimulating hormone (TSH), TH, or thyroid autoantibodies are associated with betatrophin levels.
In the study, serum betatrophin was measured in the subjects grouped as overt hypothyroidism (OH), subclinical hypothyroidism (SCH), euthyroid with isolated thyroid peroxidase antibody positivity (isolated Ab), and healthy control (HC), according to their thyroid functions.
From our results, we found that betatrophin may be associated with thyroid insufficiency but not thyroid autoimmunity.
Thus, when interpreting the results of betatrophin, thyroid functions should also be taken into consideration.
American Psychological Association (APA)
Han, Cheng& Xia, Xinghai& Liu, Aihua& Zhang, Xiaowen& Zhou, Mi& Xiong, Chuhui…[et al.]. 2016. Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098005
Modern Language Association (MLA)
Han, Cheng…[et al.]. Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098005
American Medical Association (AMA)
Han, Cheng& Xia, Xinghai& Liu, Aihua& Zhang, Xiaowen& Zhou, Mi& Xiong, Chuhui…[et al.]. Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098005
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098005