Effect of Xinjiang Uyghur Vernonia anthelmintica Willd Injection Treatment with Silicosis Fibrosis
Joint Authors
Liu, Guitao
Liu, Yingjia
Jin, Lu
Li, Cuidong
Nie, Liping
Wei, Yanhua
Wang, Wenyu
Xu, Yuhong
Nusilaiti, Nuziguli
Hua, Ping
Li, Xiujuan
Wang, Xiaohua
Wei, Wenlong
Wufuer, Hamulati
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
To observe the curative effect of VAWI on Xinjiang Uygur patients with silicosis fibrosis.
Methods.
After we diagnosed the 40 patients with the first phase of silicosis, we randomly divided them into two groups: the basic treatment group (group A, n = 20 ) and the VAWI group (group B, n = 20 ).
At the same time, we selected the age-matched healthy patients ( n = 20 ).
We applied the combined protein chip with SELDI-TOF-MS to carry out the serum analysis.
The data were analyzed throughout data preprocessing, difference in PEAK screening, hierarchical cluster analysis, and Principal Component Analysis (PCA).
We built decision tree model and predict the difference between the PEAK corresponding proteins.
Results.
The proteins peaks corresponding to name, predicted protein, and gene name were as follows: M2001_69, amyloid beta a4 protein, APP, and M2017_02, amyloid beta a4 protein, APP.
The different expression of proteins in patients with silicosis was found before and after with VAWI treatment.
The predicted proteins were as follows: M1982_50, amyloid beta a4 protein, APP; M3164_50, fibrinogen alpha chain frag, FGA; M3379_28, fibrinogen alpha chain frag, FGA; and so on.
Conclusion.
VAWI presented curative effect on patients with silicosis fibrosis via the alternation of proteins expression in serum.
American Psychological Association (APA)
Liu, Guitao& Liu, Yingjia& Jin, Lu& Li, Cuidong& Nie, Liping& Wei, Yanhua…[et al.]. 2016. Effect of Xinjiang Uyghur Vernonia anthelmintica Willd Injection Treatment with Silicosis Fibrosis. BioMed Research International،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1098010
Modern Language Association (MLA)
Liu, Guitao…[et al.]. Effect of Xinjiang Uyghur Vernonia anthelmintica Willd Injection Treatment with Silicosis Fibrosis. BioMed Research International No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1098010
American Medical Association (AMA)
Liu, Guitao& Liu, Yingjia& Jin, Lu& Li, Cuidong& Nie, Liping& Wei, Yanhua…[et al.]. Effect of Xinjiang Uyghur Vernonia anthelmintica Willd Injection Treatment with Silicosis Fibrosis. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1098010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098010