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Laser Scanning In Vivo Confocal Microscopy of Clear Grafts after Penetrating Keratoplasty
Joint Authors
Gao, Hua
Wang, Dai
Song, Peng
Wang, Shuting
Sun, Dapeng
Wang, Yuexin
Zhang, Yangyang
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To evaluate the changes of keratocytes and dendritic cells in the central clear graft by laser scanning in vivo confocal microscopy after penetrating keratoplasty (PK).
Methods.
Thirty adult subjects receiving PK at Shandong Eye Institute and with clear grafts and no sign of immune rejection after surgery were recruited into this study, and 10 healthy adults were controls.
The keratocytes and dendritic cells in the central graft were evaluated by laser scanning confocal microscopy, as well as epithelium cells, keratocytes, corneal endothelium cells, and corneal nerves (especially subepithelial plexus nerves).
Results.
Median density of subepithelial plexus nerves, keratocyte density in each layer of the stroma, and density of corneal endothelium cells were all lower in clear grafts than in controls.
The dendritic cells of five (16.7%) patients were active in Bowman’s membrane and stromal membrane of the graft after PK.
Conclusions.
Activated dendritic cells and Langerhans cells could be detected in some of the clear grafts, which indicated that the subclinical stress of immune reaction took part in the chronic injury of the clear graft after PK, even when there was no clinical rejection episode.
American Psychological Association (APA)
Wang, Dai& Song, Peng& Wang, Shuting& Sun, Dapeng& Wang, Yuexin& Zhang, Yangyang…[et al.]. 2016. Laser Scanning In Vivo Confocal Microscopy of Clear Grafts after Penetrating Keratoplasty. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098013
Modern Language Association (MLA)
Wang, Dai…[et al.]. Laser Scanning In Vivo Confocal Microscopy of Clear Grafts after Penetrating Keratoplasty. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098013
American Medical Association (AMA)
Wang, Dai& Song, Peng& Wang, Shuting& Sun, Dapeng& Wang, Yuexin& Zhang, Yangyang…[et al.]. Laser Scanning In Vivo Confocal Microscopy of Clear Grafts after Penetrating Keratoplasty. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098013
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098013