Identification of Secretory Proteins in Mycobacterium tuberculosis Using Pseudo Amino Acid Composition
Joint Authors
Ding, Hui
Lin, Hao
Chen, Wei
Chen, Xin-Xin
Tang, Hua
Yang, Huan
Zhang, Chang-Jian
Zhu, Pan-Pan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tuberculosis is killing millions of lives every year and on the blacklist of the most appalling public health problems.
Recent findings suggest that secretory protein of Mycobacterium tuberculosis may serve the purpose of developing specific vaccines and drugs due to their antigenicity.
Responding to global infectious disease, we focused on the identification of secretory proteins in Mycobacterium tuberculosis.
A novel method called MycoSec was designed by incorporating g -gap dipeptide compositions into pseudo amino acid composition.
Analysis of variance-based technique was applied in the process of feature selection and a total of 374 optimal features were obtained and used for constructing the final predicting model.
In the jackknife test, MycoSec yielded a good performance with the area under the receiver operating characteristic curve of 0.93, demonstrating that the proposed system is powerful and robust.
For user’s convenience, the web server MycoSec was established and an obliging manual on how to use it was provided for getting around any trouble unnecessary.
American Psychological Association (APA)
Yang, Huan& Tang, Hua& Chen, Xin-Xin& Zhang, Chang-Jian& Zhu, Pan-Pan& Ding, Hui…[et al.]. 2016. Identification of Secretory Proteins in Mycobacterium tuberculosis Using Pseudo Amino Acid Composition. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098113
Modern Language Association (MLA)
Yang, Huan…[et al.]. Identification of Secretory Proteins in Mycobacterium tuberculosis Using Pseudo Amino Acid Composition. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1098113
American Medical Association (AMA)
Yang, Huan& Tang, Hua& Chen, Xin-Xin& Zhang, Chang-Jian& Zhu, Pan-Pan& Ding, Hui…[et al.]. Identification of Secretory Proteins in Mycobacterium tuberculosis Using Pseudo Amino Acid Composition. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098113