Association between Serum Ferritin and Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Joint Authors
Zhu, Boqian
Hou, Jiantong
Gong, Yaoyao
Yan, Gaoliang
Wang, Qingjie
Wang, Dong
Qiao, Yong
Chen, Yifei
Tang, Chengchun
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background and Aims.
CIN is a major and serious complication following PCI in patients with ACS.
It is unclear whether a higher serum ferritin level is associated with an increased risk of CIN in high-risk patients.
Thus, we conducted this study to assess the predictive value of SF for the risk of CIN after PCI.
Methods.
We prospectively examined SF levels in 548 patients with ACS before undergoing PCI.
Multivariate logistic regression analysis was used to analyze the independent risk factors for CIN.
The ROC analysis was performed to evaluate the predictive value of SF for CIN.
Results.
CIN occurred in 96 patients.
Baseline SF was higher in patients who developed CIN compared to those who did not ( 257.05 ± 93.98 versus 211.67 ± 106.65 ; P < 0.001 ).
Multivariate logistic regression analysis showed that SF was an independent predictor of CIN (OR, 1.008; 95% CI, 1.003–1.013; P = 0.002 ).
The area under ROC curve for SF was 0.629, and SF > 180.9 μg/L predicted CIN with sensitivity of 80.2% and specificity of 41.4%.
Conclusion.
Our data show that a higher SF level was significantly associated with an increased risk of CIN after PCI.
American Psychological Association (APA)
Zhu, Boqian& Hou, Jiantong& Gong, Yaoyao& Yan, Gaoliang& Wang, Qingjie& Wang, Dong…[et al.]. 2016. Association between Serum Ferritin and Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098115
Modern Language Association (MLA)
Zhu, Boqian…[et al.]. Association between Serum Ferritin and Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098115
American Medical Association (AMA)
Zhu, Boqian& Hou, Jiantong& Gong, Yaoyao& Yan, Gaoliang& Wang, Qingjie& Wang, Dong…[et al.]. Association between Serum Ferritin and Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098115
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098115