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Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity
Joint Authors
Al-Majedy, Yasameen K.
Kadhum, Abdul Amir H.
al-Amiery, Ahmed A.
Mohamad, Abu Bakar
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The problem of bacteria resistance to many known agents has inspired scientists and researchers to discover novel efficient antibacterial drugs.
Three rapid, clean, and highly efficient methods were developed for one-pot synthesis of 7-(aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives.
Three components are condensed in the synthesis, 4-hydroxycoumarin, 5,5-dimethyl-1,3-cyclohexanedione, and aromatic aldehydes, using tetrabutylammonium bromide (TBAB), diammonium hydrogen phosphate (DAHP), or ferric chloride (FeCl3), respectively.
Each method has different reaction mechanisms according to the catalyst.
The present methods have advantages, including one-pot synthesis, excellent yields, short reaction times, and easy isolation of product.
All catalysts utilized in our study could be reused several times without losing their catalytic efficiency.
All synthesized compounds were fully characterized and evaluated for their antibacterial activity.
American Psychological Association (APA)
Al-Majedy, Yasameen K.& al-Amiery, Ahmed A.& Kadhum, Abdul Amir H.& Mohamad, Abu Bakar. 2016. Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098236
Modern Language Association (MLA)
Al-Majedy, Yasameen K.…[et al.]. Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1098236
American Medical Association (AMA)
Al-Majedy, Yasameen K.& al-Amiery, Ahmed A.& Kadhum, Abdul Amir H.& Mohamad, Abu Bakar. Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098236