The Influence of Humidity on Assessing Irritation Threshold of Ammonia
Joint Authors
Sucker, Kirsten
Hoffmeyer, Frank
Jettkant, Birger
Berresheim, Hans
Monsé, Christian
Brüning, Thomas
Bünger, Jürgen
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A large number of occupational exposure limit values (OELs) are based on avoiding of sensory irritation of the eyes and the upper respiratory tract.
In order to investigate the chemosensory effect range of a chemical, odor and sensory irritation thresholds (lateralization thresholds, LTs) can be assessed.
Humidity affects olfactory function and thus influences odor thresholds; however, a similar effect has not been shown for sensory irritation thresholds.
The purpose of the present study was to explore whether LTs for ammonia vapor vary depending on the water vapor content of the inspired stimulus.
Eight healthy nonsmoking volunteers were simultaneously exposed to ammonia vapor through one nostril and clean air through the other and were asked to determine which nostril received the chemical.
Within experimental runs, ascending ammonia concentrations (60–350 ppm) that were either dry or humidified were administered at fixed time intervals.
Geometric mean LTs obtained at wet (181 ppm) or dry (172 ppm) conditions did not differ significantly (P = 0.19) and were within the range of those reported by previous studies.
These results suggest that humidity is not a critical factor in determining sensory irritation thresholds for ammonia, and future studies will examine if these findings are transferable to sensory irritation thresholds for other chemicals.
American Psychological Association (APA)
Monsé, Christian& Sucker, Kirsten& Hoffmeyer, Frank& Jettkant, Birger& Berresheim, Hans& Bünger, Jürgen…[et al.]. 2016. The Influence of Humidity on Assessing Irritation Threshold of Ammonia. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098332
Modern Language Association (MLA)
Monsé, Christian…[et al.]. The Influence of Humidity on Assessing Irritation Threshold of Ammonia. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1098332
American Medical Association (AMA)
Monsé, Christian& Sucker, Kirsten& Hoffmeyer, Frank& Jettkant, Birger& Berresheim, Hans& Bünger, Jürgen…[et al.]. The Influence of Humidity on Assessing Irritation Threshold of Ammonia. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098332
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098332