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Sertoli Cell-Only Syndrome: Behind the Genetic Scenes
Joint Authors
Stouffs, Katrien
Gheldof, Alexander
Tournaye, Herman
Vandermaelen, Deborah
Bonduelle, Maryse
Lissens, Willy
Seneca, Sara
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Sertoli cell-only syndrome is defined by the complete absence of germ cells in testicular tissues and always results in male infertility.
The aetiology often remains unknown.
In this paper, we have investigated possible causes of Sertoli cell-only syndrome with a special focus on genetic causes.
Our results show that, for a large part of the patients (>23% in an unselected group), the sex chromosomes are involved.
The majority of patients had a Klinefelter syndrome, followed by patients with Yq microdeletions.
Array comparative genomic hybridization in a selected group of “idiopathic patients” showed no known infertility related copy number variations.
American Psychological Association (APA)
Stouffs, Katrien& Gheldof, Alexander& Tournaye, Herman& Vandermaelen, Deborah& Bonduelle, Maryse& Lissens, Willy…[et al.]. 2016. Sertoli Cell-Only Syndrome: Behind the Genetic Scenes. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098404
Modern Language Association (MLA)
Stouffs, Katrien…[et al.]. Sertoli Cell-Only Syndrome: Behind the Genetic Scenes. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1098404
American Medical Association (AMA)
Stouffs, Katrien& Gheldof, Alexander& Tournaye, Herman& Vandermaelen, Deborah& Bonduelle, Maryse& Lissens, Willy…[et al.]. Sertoli Cell-Only Syndrome: Behind the Genetic Scenes. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098404
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098404