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Effect of Associated Autoimmune Diseases on Type 1 Diabetes Mellitus Incidence and Metabolic Control in Children and Adolescents
Joint Authors
Krzewska, Aleksandra
Ben-Skowronek, Iwona
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases developing in childhood.
The incidence of the disease in children increases for unknown reasons at a rate from 3 to 5% every year worldwide.
The background of T1DM is associated with the autoimmune process of pancreatic beta cell destruction, which leads to absolute insulin deficiency and organ damage.
Complex interactions between environmental and genetic factors contribute to the development of T1DM in genetically predisposed patients.
The T1DM-inducing autoimmune process can also affect other organs, resulting in development of additional autoimmune diseases in the patient, thereby impeding diabetes control.
The most common T1DM comorbidities include autoimmune thyroid diseases, celiac disease, and autoimmune gastritis; additionally, diabetes can be a component of PAS (Polyglandular Autoimmune Syndrome).
The aim of this review is to assess the prevalence of T1DM-associated autoimmune diseases in children and adolescents and their impact on the course of T1DM.
We also present suggestions concerning screening tests.
American Psychological Association (APA)
Krzewska, Aleksandra& Ben-Skowronek, Iwona. 2016. Effect of Associated Autoimmune Diseases on Type 1 Diabetes Mellitus Incidence and Metabolic Control in Children and Adolescents. BioMed Research International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1098413
Modern Language Association (MLA)
Krzewska, Aleksandra& Ben-Skowronek, Iwona. Effect of Associated Autoimmune Diseases on Type 1 Diabetes Mellitus Incidence and Metabolic Control in Children and Adolescents. BioMed Research International No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1098413
American Medical Association (AMA)
Krzewska, Aleksandra& Ben-Skowronek, Iwona. Effect of Associated Autoimmune Diseases on Type 1 Diabetes Mellitus Incidence and Metabolic Control in Children and Adolescents. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1098413
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098413