Serum Biochemistry of Lumpy Skin Disease Virus-Infected Cattle
Joint Authors
Avci, Oguzhan
Şevik, Murat
Doğan, Müge
İnce, Ömer Barış
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Lumpy skin disease is an economically important poxvirus disease of cattle.
Vaccination is the main method of control but sporadic outbreaks have been reported in Turkey.
This study was carried out to determine the changes in serum biochemical values of cattle naturally infected with lumpy skin disease virus (LSDV).
For this study, blood samples in EDTA, serum samples, and nodular skin lesions were obtained from clinically infected animals ( n = 15 ) whereas blood samples in EDTA and serum samples were collected from healthy animals ( n = 15 ).
A quantitative real-time PCR method was used to detect Capripoxvirus (CaPV) DNA in clinical samples.
A real-time PCR high-resolution melt assay was performed to genotype CaPVs.
Serum cardiac, hepatic, and renal damage markers and lipid metabolism products were measured by autoanalyzer.
LSDV nucleic acid was detected in all samples which were obtained from clinically infected cattle.
The results of serum biochemical analysis showed that aspartate aminotransferase, alkaline phosphatase, total protein, and creatinine concentrations were markedly increased in serum from infected animals.
However, there were no significant differences in the other biochemical parameters evaluated.
The results of the current study suggest that liver and kidney failures occur during LSDV infection.
These findings may help in developing effective treatment strategies in LSDV infection.
American Psychological Association (APA)
Şevik, Murat& Avci, Oguzhan& Doğan, Müge& İnce, Ömer Barış. 2016. Serum Biochemistry of Lumpy Skin Disease Virus-Infected Cattle. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098422
Modern Language Association (MLA)
Şevik, Murat…[et al.]. Serum Biochemistry of Lumpy Skin Disease Virus-Infected Cattle. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098422
American Medical Association (AMA)
Şevik, Murat& Avci, Oguzhan& Doğan, Müge& İnce, Ömer Barış. Serum Biochemistry of Lumpy Skin Disease Virus-Infected Cattle. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098422