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Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases
Joint Authors
Aydoğmuş, Çiğdem
Türel, Özden
Kazanci, Selcen
Gonen, Ismail
Karaoglan, Emel
Siraneci, Rengin
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Tuberculosis (TB) still remains a growing public health problem globally.
TB in children is often diagnosed clinically.
Methods.
We conducted a retrospective chart review of children with TB from November 2004 through December 2010 to determine the appropriateness of using contact history and diagnostic testing.
Results.
A total of 250 children with TB were identified.
One hundred and sixty-two children had only pulmonary disease while 39 had features of both extrapulmonary and pulmonary TB.
Mean age was 7.8 years.
Thirty-six patients had known contacts.
The index case/cases were first-degree relatives in 75%.
Sixteen patients who were symptomless were yielded by contact investigation of newly identified TB cases.
Tuberculin skin test positivity was 53.3%.
Acid-fast bacilli smear positivity was 13.1%, and culture positivity was 18.7%.
Twenty-six patients had histopathology of nonrespiratory specimens (lymph nodes and other tissues) showing granulomatous inflammation and caseous necrosis consistent with TB.
Conclusions.
Presence of contact history directed us to search for TB in children with nonspecific symptoms even if physical examinations were normal.
Some children who were close contacts to TB cases were identified to have TB before development of symptoms.
American Psychological Association (APA)
Türel, Özden& Kazanci, Selcen& Gonen, Ismail& Aydoğmuş, Çiğdem& Karaoglan, Emel& Siraneci, Rengin. 2016. Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098625
Modern Language Association (MLA)
Türel, Özden…[et al.]. Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098625
American Medical Association (AMA)
Türel, Özden& Kazanci, Selcen& Gonen, Ismail& Aydoğmuş, Çiğdem& Karaoglan, Emel& Siraneci, Rengin. Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098625