Gray Matter Atrophy within the Default Mode Network of Fibromyalgia: A Meta-Analysis of Voxel-Based Morphometry Studies
Joint Authors
Lin, Chemin
Lee, Shwu-Hua
Weng, Hsu-Huei
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Over the years, studies have demonstrated morphological changes in the brain of fibromyalgia (FMS).
We aimed to conduct a coordinate-based meta-analytic research through systemic review on voxel-based morphometry (VBM) imaging results to identify consistent gray matter (GM) difference between FMS patients and healthy subjects.
We performed a comprehensive literature search in PubMed (January 2000–December 2015) and included six VBM publication on FMS.
Stereotactic data were extracted from 180 patients of FMS and 123 healthy controls.
By means of activation likelihood estimation (ALE) technique, regional GM reduction in left medial prefrontal cortex and right dorsal posterior cingulate cortex was identified.
Both regions are within the default mode network.
In conclusion, the gray matter deficit is related to the both affective and nonaffective components of pain processing.
This result also provided the neuroanatomical correlates for emotional and cognitive symptoms in FMS.
American Psychological Association (APA)
Lin, Chemin& Lee, Shwu-Hua& Weng, Hsu-Huei. 2016. Gray Matter Atrophy within the Default Mode Network of Fibromyalgia: A Meta-Analysis of Voxel-Based Morphometry Studies. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098764
Modern Language Association (MLA)
Lin, Chemin…[et al.]. Gray Matter Atrophy within the Default Mode Network of Fibromyalgia: A Meta-Analysis of Voxel-Based Morphometry Studies. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1098764
American Medical Association (AMA)
Lin, Chemin& Lee, Shwu-Hua& Weng, Hsu-Huei. Gray Matter Atrophy within the Default Mode Network of Fibromyalgia: A Meta-Analysis of Voxel-Based Morphometry Studies. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098764
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098764