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Integrative Characterization of Toxic Response of Zebra Fish (Danio rerio) to Deltamethrin Based on AChE Activity and Behavior Strength
Joint Authors
Ren, Zongming
Qi, Li
Pan, Hongwei
Ren, Qing
Zhang, Tingting
Li, Shangge
Yang, Meiyi
Xu, Shiguo
Chon, Tae-Soo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
In order to characterize the toxic response of zebra fish (Danio rerio) to Deltamethrin (DM), behavior strength (BS) and muscle AChE activity of zebra fish were investigated.
The results showed that the average values of both BS and AChE activity showed a similarly decreased tendency as DM concentration increased, which confirmed the dose-effect relationship, and high and low levels of AChE and BS partly matched low and high levels of exposure concentrations in self-organizing map.
These indicated that AChE and BS had slight different aspects of toxicity although overall trend was similar.
Behavior activity suggested a possibility of reviving circadian rhythm in test organisms after exposure to the chemical in lower concentration (0.1 TU).
This type of rhythm disappeared in higher concentrations (1.0 TU and 2.0 TU).
Time series trend analysis of BS and AChE showed an evident time delayed effect of AChE, and a 2 h AChE inhibition delay with higher correlation coefficients (r) in different treatments was observed.
It was confirmed that muscle AChE inhibition of zebra fish is a factor for swimming behavior change, though there was a 2 h delay, and other factors should be investigated to illustrate the detailed behavior response mechanism.
American Psychological Association (APA)
Ren, Qing& Zhang, Tingting& Li, Shangge& Ren, Zongming& Yang, Meiyi& Pan, Hongwei…[et al.]. 2016. Integrative Characterization of Toxic Response of Zebra Fish (Danio rerio) to Deltamethrin Based on AChE Activity and Behavior Strength. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098765
Modern Language Association (MLA)
Ren, Qing…[et al.]. Integrative Characterization of Toxic Response of Zebra Fish (Danio rerio) to Deltamethrin Based on AChE Activity and Behavior Strength. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098765
American Medical Association (AMA)
Ren, Qing& Zhang, Tingting& Li, Shangge& Ren, Zongming& Yang, Meiyi& Pan, Hongwei…[et al.]. Integrative Characterization of Toxic Response of Zebra Fish (Danio rerio) to Deltamethrin Based on AChE Activity and Behavior Strength. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098765
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098765