Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study
Joint Authors
Deng, Jun
Feng, Yuanming
Zhang, Ying
Ming, Xin
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-09
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
A novel treatment modality termed energy modulated photon radiotherapy (EMXRT) was investigated.
The first step of EMXRT was to determine beam energy for each gantry angle/anatomy configuration from a pool of photon energy beams (2 to 10 MV) with a newly developed energy selector.
An inverse planning system using gradient search algorithm was then employed to optimize photon beam intensity of various beam energies based on presimulated Monte Carlo pencil beam dose distributions in patient anatomy.
Finally, 3D dose distributions in six patients of different tumor sites were simulated with Monte Carlo method and compared between EMXRT plans and clinical IMRT plans.
Compared to current IMRT technique, the proposed EMXRT method could offer a better paradigm for the radiotherapy of lung cancers and pediatric brain tumors in terms of normal tissue sparing and integral dose.
For prostate, head and neck, spine, and thyroid lesions, the EMXRT plans were generally comparable to the IMRT plans.
Our feasibility study indicated that lower energy (<6 MV) photon beams could be considered in modern radiotherapy treatment planning to achieve a more personalized care for individual patient with dosimetric gains.
American Psychological Association (APA)
Zhang, Ying& Feng, Yuanming& Ming, Xin& Deng, Jun. 2016. Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1098769
Modern Language Association (MLA)
Zhang, Ying…[et al.]. Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study. BioMed Research International No. 2016 (2016), pp.1-16.
https://search.emarefa.net/detail/BIM-1098769
American Medical Association (AMA)
Zhang, Ying& Feng, Yuanming& Ming, Xin& Deng, Jun. Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1098769
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098769