Djulis (Chenopodium formosanum Koidz.) Water Extract and Its Bioactive Components Ameliorate Dermal Damage in UVB-Irradiated Skin Models
Joint Authors
Hong, Yong-Han
Huang, Ya-Ling
Liu, Yao-Cheng
Tsai, Pi-Jen
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Dermal photoaging is a condition of skin suffering inappropriate ultraviolet (UV) exposure and exerts inflammation, tissue alterations, redness, swelling, and uncomfortable feelings.
Djulis (Chenopodium formosanum Koidz.) is a cereal food and its antioxidant and pigment constituents may provide skin protection from photoaging, but it still lacks proved experiments.
In this study, protective effects of djulis extract (CFE) on UVB-irradiated skin were explored.
The results showed that HaCaT cells with 150 μg/mL CFE treatment had higher survival and less production of interleukin- (IL-) 6, matrix metalloprotease- (MMP-) 1, and reactive oxygen species (ROS) in UVB-irradiated conditions.
Subsequently, in animal studies, mice supplemented with CFE (100 mg/kg BW) were under UVB irradiation and had thinner epidermis and lower IL-6 levels in skin layer.
These data demonstrate that bioactive compounds possessing the potency of antiphotoaging exist in CFE.
Following that, we found rutin and chlorogenic acid (10–100 μM) could significantly increase cell viability and decrease the production of IL-6 in UVB models.
Additionally, djulis pigment-betanin has no effect of increasing cell viability in this study.
Our findings suggest CFE can protect skin against UV-induced damage and this protection is mainly from contributions of rutin and chlorogenic acid.
American Psychological Association (APA)
Hong, Yong-Han& Huang, Ya-Ling& Liu, Yao-Cheng& Tsai, Pi-Jen. 2016. Djulis (Chenopodium formosanum Koidz.) Water Extract and Its Bioactive Components Ameliorate Dermal Damage in UVB-Irradiated Skin Models. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098775
Modern Language Association (MLA)
Tsai, Pi-Jen…[et al.]. Djulis (Chenopodium formosanum Koidz.) Water Extract and Its Bioactive Components Ameliorate Dermal Damage in UVB-Irradiated Skin Models. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098775
American Medical Association (AMA)
Hong, Yong-Han& Huang, Ya-Ling& Liu, Yao-Cheng& Tsai, Pi-Jen. Djulis (Chenopodium formosanum Koidz.) Water Extract and Its Bioactive Components Ameliorate Dermal Damage in UVB-Irradiated Skin Models. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098775
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098775