In Vivo Laser Scanning Confocal Microscopy of Human Meibomian Glands in Aging and Ocular Surface Diseases
Joint Authors
Mastropasqua, Rodolfo
Ciancaglini, Marco
Brescia, Lorenza
Di Staso, Federico
Fasanella, Vincenzo
Agnifili, Luca
Mastropasqua, Leonardo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Meibomian glands (MGs) play a crucial role in the ocular surface homeostasis by providing lipids to the superficial tear film.
Their dysfunction destabilizes the tear film leading to a progressive loss of the ocular surface equilibrium and increasing the risk for dry eye.
In fact, nowadays, the meibomian gland dysfunction is one of the leading causes of dry eye.
Over the past decades, MGs have been mainly studied by using meibography, which, however, cannot image the glandular structure at a cellular level.
The diffusion of the in vivo laser scanning confocal microscopy (LSCM) provided a new approach for the structural assessment of MGs permitting a major step in the noninvasive evaluation of these structures.
LSCM is capable of showing MGs modifications during aging and in the most diffuse ocular surface diseases such as dry eye, allergy, and autoimmune conditions and in the drug-induced ocular surface disease.
On the other hand, LSCM may help clinicians in monitoring the tissue response to therapy.
In this review, we summarized the current knowledge about the role of in vivo LSCM in the assessment of MGs during aging and in the most diffuse ocular surface diseases.
American Psychological Association (APA)
Fasanella, Vincenzo& Agnifili, Luca& Mastropasqua, Rodolfo& Brescia, Lorenza& Di Staso, Federico& Ciancaglini, Marco…[et al.]. 2016. In Vivo Laser Scanning Confocal Microscopy of Human Meibomian Glands in Aging and Ocular Surface Diseases. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098788
Modern Language Association (MLA)
Fasanella, Vincenzo…[et al.]. In Vivo Laser Scanning Confocal Microscopy of Human Meibomian Glands in Aging and Ocular Surface Diseases. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098788
American Medical Association (AMA)
Fasanella, Vincenzo& Agnifili, Luca& Mastropasqua, Rodolfo& Brescia, Lorenza& Di Staso, Federico& Ciancaglini, Marco…[et al.]. In Vivo Laser Scanning Confocal Microscopy of Human Meibomian Glands in Aging and Ocular Surface Diseases. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098788
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098788