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Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study
Joint Authors
Zhang, Chun-yan
Tian, Ya-Ping
Wang, Yurong
Fu, Lei
Jia, Qian
Yu, Hao
Zhang, Pengjun
Huang, Xueliang
He, Kunlun
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Changes of N-terminal probrain natriuretic peptide (NT-proBNP) have been studied whether in the long term or the short term in patients of acute heart failure (AHF); however, changes of NT-proBNP in the first five days and their association with other factors have not been investigated.
Aims.
To describe the dynamic changes of relevant laboratory indexes in the first five days between different outcomes of AHF patients and their associations.
Methods and Results.
284 AHF with dynamic values recorded were analyzed.
Changes of NT-proBNP, troponin T, and C-reactive protein were different between patients with different outcomes, with higher values in adverse group than in control group at the same time points ( p < 0.05 ).
Then, prognostic use and risk stratification of NT-proBNP were assessed by receiver-operating characteristic curve and logistic regression.
NT-proBNP levels at day 3 showed the best prognostic power (area under the curve = 0.730, 95% confidence interval (CI): 0.657 to 0.794) and was an independent risk factor for adverse outcome (odds ratio, OR: 2.185, 95% CI: 1.584–3.015).
Classified changes of NT-proBNP may be predictive for adverse outcomes in AHF patients.
Conclusions.
Sequential monitoring of laboratory indexes within the first 5 days may be helpful for management of AHF patients.
American Psychological Association (APA)
Wang, Yurong& Fu, Lei& Jia, Qian& Yu, Hao& Zhang, Pengjun& Zhang, Chun-yan…[et al.]. 2016. Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098801
Modern Language Association (MLA)
Wang, Yurong…[et al.]. Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098801
American Medical Association (AMA)
Wang, Yurong& Fu, Lei& Jia, Qian& Yu, Hao& Zhang, Pengjun& Zhang, Chun-yan…[et al.]. Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098801