Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study

Joint Authors

Zhang, Chun-yan
Tian, Ya-Ping
Wang, Yurong
Fu, Lei
Jia, Qian
Yu, Hao
Zhang, Pengjun
Huang, Xueliang
He, Kunlun

Source

BioMed Research International

Issue

Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2016-04-06

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Medicine

Abstract EN

Background.

Changes of N-terminal probrain natriuretic peptide (NT-proBNP) have been studied whether in the long term or the short term in patients of acute heart failure (AHF); however, changes of NT-proBNP in the first five days and their association with other factors have not been investigated.

Aims.

To describe the dynamic changes of relevant laboratory indexes in the first five days between different outcomes of AHF patients and their associations.

Methods and Results.

284 AHF with dynamic values recorded were analyzed.

Changes of NT-proBNP, troponin T, and C-reactive protein were different between patients with different outcomes, with higher values in adverse group than in control group at the same time points ( p < 0.05 ).

Then, prognostic use and risk stratification of NT-proBNP were assessed by receiver-operating characteristic curve and logistic regression.

NT-proBNP levels at day 3 showed the best prognostic power (area under the curve = 0.730, 95% confidence interval (CI): 0.657 to 0.794) and was an independent risk factor for adverse outcome (odds ratio, OR: 2.185, 95% CI: 1.584–3.015).

Classified changes of NT-proBNP may be predictive for adverse outcomes in AHF patients.

Conclusions.

Sequential monitoring of laboratory indexes within the first 5 days may be helpful for management of AHF patients.

American Psychological Association (APA)

Wang, Yurong& Fu, Lei& Jia, Qian& Yu, Hao& Zhang, Pengjun& Zhang, Chun-yan…[et al.]. 2016. Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098801

Modern Language Association (MLA)

Wang, Yurong…[et al.]. Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098801

American Medical Association (AMA)

Wang, Yurong& Fu, Lei& Jia, Qian& Yu, Hao& Zhang, Pengjun& Zhang, Chun-yan…[et al.]. Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098801

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1098801