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Genetic Characterization of a Novel Mutant of Peste Des Petits Ruminants Virus Isolated from Capra ibex in China during 2015
Joint Authors
Zhang, Xiangle
Zheng, Haixue
Zhang, Xiaocui
Adili, Gulizhati
Huang, Jiong
Du, Xiaoli
Li, Pengfei
Zheng, Xueguang
Liu, Xiangtao
Xue, Qinghong
Zhu, Zixiang
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Peste des petits ruminants virus (PPRV) is the causative agent of peste des petits ruminants (PPR).
The spread of PPR often causes severe economic losses.
Therefore, special attention should be paid to the surveillance of PPR emergence, spread, and geographic distribution.
Here we describe a novel mutant of PPRV China/XJBZ/2015 that was isolated from Capra ibex in Xinjiang province in China 2015.
The sequence analysis and phylogenetic assessment indicate that China/XJBZ/2015 belongs to lineage IV, being closely related to China/XJYL/2013 strain.
Interestingly, the V protein sequence of China/XJBZ/2015 showed lower homology with other Chinese PPRVs isolated during 2013 to 2014 (94%~95%), whereas it shared 100% identity with three Tibet strains isolated in China 2007.
The 3′ UTR, V gene, and C gene were determined to be highly variable.
Besides, 29 PPR genomic sequences available in GenBank were analyzed in this study.
It is the first time to use PPRV genomic sequences to classify the different lineages which confirmed the lineage clustering of PPRVs using N gene 255 bp fragments and F gene 322 bp fragments.
In conclusion, our findings indicate that the PPRVs continue to evolve in China, and some new mutations have emerged.
American Psychological Association (APA)
Zhu, Zixiang& Zhang, Xiaocui& Adili, Gulizhati& Huang, Jiong& Du, Xiaoli& Zhang, Xiangle…[et al.]. 2016. Genetic Characterization of a Novel Mutant of Peste Des Petits Ruminants Virus Isolated from Capra ibex in China during 2015. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098837
Modern Language Association (MLA)
Zhu, Zixiang…[et al.]. Genetic Characterization of a Novel Mutant of Peste Des Petits Ruminants Virus Isolated from Capra ibex in China during 2015. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1098837
American Medical Association (AMA)
Zhu, Zixiang& Zhang, Xiaocui& Adili, Gulizhati& Huang, Jiong& Du, Xiaoli& Zhang, Xiangle…[et al.]. Genetic Characterization of a Novel Mutant of Peste Des Petits Ruminants Virus Isolated from Capra ibex in China during 2015. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1098837
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098837