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Molecular Background of miRNA Role in Asthma and COPD: An Updated Insight
Joint Authors
Wieczfinska, Joanna
Szymczak, Izabela
Pawliczak, Rafal
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Inflammatory airway diseases are a significant health problems requiring new approaches to the existing therapies and addressing fundamental issues.
Difficulties in developing effective therapeutic strategies might be caused by lack of understanding of their exact molecular mechanism.
MicroRNAs (miRNAs) are a class of regulators that already revolutionized the view of gene expression regulation.
A cumulating number of investigations show a pivotal role of miRNAs in the pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), or airway remodeling through the regulation of many pathways involved in their pathogenesis.
Expression changes of several miRNAs have also been found to play a role in the development and/or improvement in asthma or COPD.
Still, relatively little is known about the role of miRNAs in inflammatory disorders.
The microRNA profiles may differ depending on the cell type or antigen-presenting cell.
Based on the newest literature, this review discusses the current knowledge concerning miRNA contribution and influence on lung inflammation and chosen inflammatory airway diseases: asthma and COPD.
American Psychological Association (APA)
Szymczak, Izabela& Wieczfinska, Joanna& Pawliczak, Rafal. 2016. Molecular Background of miRNA Role in Asthma and COPD: An Updated Insight. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098851
Modern Language Association (MLA)
Szymczak, Izabela…[et al.]. Molecular Background of miRNA Role in Asthma and COPD: An Updated Insight. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098851
American Medical Association (AMA)
Szymczak, Izabela& Wieczfinska, Joanna& Pawliczak, Rafal. Molecular Background of miRNA Role in Asthma and COPD: An Updated Insight. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098851
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098851