Whole Blood Transcriptome Sequencing Reveals Gene Expression Differences between Dapulian and Landrace Piglets
Joint Authors
Hu, Jiaqing
Yang, Dandan
Chen, Wei
Li, Chuanhao
Wang, Yandong
Zeng, Yongqing
Wang, Hui
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
There is little genomic information regarding gene expression differences at the whole blood transcriptome level of different pig breeds at the neonatal stage.
To solve this, we characterized differentially expressed genes (DEGs) in the whole blood of Dapulian (DPL) and Landrace piglets using RNA-seq (RNA-sequencing) technology.
In this study, 83 DEGs were identified between the two breeds.
Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses identified immune response and metabolism as the most commonly enriched terms and pathways in the DEGs.
Genes related to immunity and lipid metabolism were more highly expressed in the DPL piglets, while genes related to body growth were more highly expressed in the Landrace piglets.
Additionally, the DPL piglets had twofold more single nucleotide polymorphisms (SNPs) and alternative splicing (AS) than the Landrace piglets.
These results expand our knowledge of the genes transcribed in the piglet whole blood of two breeds and provide a basis for future research of the molecular mechanisms underlying the piglet differences.
American Psychological Association (APA)
Hu, Jiaqing& Yang, Dandan& Chen, Wei& Li, Chuanhao& Wang, Yandong& Zeng, Yongqing…[et al.]. 2016. Whole Blood Transcriptome Sequencing Reveals Gene Expression Differences between Dapulian and Landrace Piglets. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098882
Modern Language Association (MLA)
Hu, Jiaqing…[et al.]. Whole Blood Transcriptome Sequencing Reveals Gene Expression Differences between Dapulian and Landrace Piglets. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1098882
American Medical Association (AMA)
Hu, Jiaqing& Yang, Dandan& Chen, Wei& Li, Chuanhao& Wang, Yandong& Zeng, Yongqing…[et al.]. Whole Blood Transcriptome Sequencing Reveals Gene Expression Differences between Dapulian and Landrace Piglets. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1098882
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098882