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Assessment of Serum Concentrations of Ghrelin, Obestatin, Omentin-1, and Apelin in Children with Type 1 Diabetes
Joint Authors
Polkowska, Agnieszka
Szczepaniak, Izabela
Bossowski, Artur
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The increasing knowledge on the functions of gastric peptides and adipokines in the body allows the assumption of their major role linking the process of food intake, nutritional status, and body growth, largely through the regulation of glucose metabolism and insulin resistance.
The aim of the study was the assessment of serum levels of selected gastric peptides and adipocytokines in children with type 1 diabetes, with respect to the disease duration.
The study involved 80 children aged 4–18 years (M/F -37/43).
Children with type 1 diabetes (n=46) were compared to the control group (n=34).
The study group was divided into 4 subgroups: (I) patients with newly diagnosed type 1 diabetes, after an episode of ketoacidosis (n=10), (II) patients with type 1 diabetes of duration no longer than 5 years (n=9), (III) patients with 5 to 10 years of DT1 (n=20), and (IV) patients with type 1 diabetes of duration longer than 10 years (n=7).
The concentrations of gastric peptide and adipocytokines across all subgroups were lower than in the control group.
The differences were statistically significant (p<0.0001), which may be of importance in the development of the disease complications.
American Psychological Association (APA)
Polkowska, Agnieszka& Szczepaniak, Izabela& Bossowski, Artur. 2016. Assessment of Serum Concentrations of Ghrelin, Obestatin, Omentin-1, and Apelin in Children with Type 1 Diabetes. BioMed Research International،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1099041
Modern Language Association (MLA)
Polkowska, Agnieszka…[et al.]. Assessment of Serum Concentrations of Ghrelin, Obestatin, Omentin-1, and Apelin in Children with Type 1 Diabetes. BioMed Research International No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1099041
American Medical Association (AMA)
Polkowska, Agnieszka& Szczepaniak, Izabela& Bossowski, Artur. Assessment of Serum Concentrations of Ghrelin, Obestatin, Omentin-1, and Apelin in Children with Type 1 Diabetes. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1099041
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099041