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Role of Macrophages in the Repair Process during the Tissue Migrating and Resident Helminth Infections
Joint Authors
Morales-Montor, Jorge
Faz-López, Berenice
Terrazas, Luis I.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-25
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The Th1/Th2/Th17 balance is a fundamental feature in the regulation of the inflammatory microenvironment during helminth infections, and an imbalance in this paradigm greatly contributes to inflammatory disorders.
In some cases of helminthiasis, an initial Th1 response could occur during the early phases of infection (acute), followed by a Th2 response that prevails in chronic infections.
During the late phase of infection, alternatively activated macrophages (AAMs) are important to counteract the inflammation caused by the Th1/Th17 response and larval migration, limiting damage and repairing the tissue affected.
Macrophages are the archetype of phagocytic cells, with the primary role of pathogen destruction and antigen presentation.
Nevertheless, other subtypes of macrophages have been described with important roles in tissue repair and immune regulation.
These types of macrophages challenge the classical view of macrophages activated by an inflammatory response.
The role of these subtypes of macrophages during helminthiasis is a controversial topic in immunoparasitology.
Here, we analyze some of the studies regarding the role of AAMs in tissue repair during the tissue migration of helminths.
American Psychological Association (APA)
Faz-López, Berenice& Morales-Montor, Jorge& Terrazas, Luis I.. 2016. Role of Macrophages in the Repair Process during the Tissue Migrating and Resident Helminth Infections. BioMed Research International،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1099104
Modern Language Association (MLA)
Faz-López, Berenice…[et al.]. Role of Macrophages in the Repair Process during the Tissue Migrating and Resident Helminth Infections. BioMed Research International No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1099104
American Medical Association (AMA)
Faz-López, Berenice& Morales-Montor, Jorge& Terrazas, Luis I.. Role of Macrophages in the Repair Process during the Tissue Migrating and Resident Helminth Infections. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1099104
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099104